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4-Hydroxy-3-methylbenzoic acid

Also known as: 3-Methyl-4-hydroxybenzoic acid, 4-Hydroxy-m-toluic acid, 4-Carboxy-o-cresol, Benzoic acid, 4-hydroxy-3-methyl-, 4-HYDROXY-3-METHYLBENZOIC ACID hemihydrate, 4-Hydroxy-3-methylbenzoic acid hydrate, AKOS BBS-00004298, EINECS 207-890-1, MFCD00270105

4-Hydroxy-3-methylbenzoic acid (CAS 499-76-3) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C8H8O3 and a molecular weight of 152.147 g/mol. Key properties include a melting point of 173-177 °C, a boiling point of 331.3±30.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 168.4±21.1 °C. It is classified under GHS with signal word Danger and hazard statements H302 — Harmful if swallowed, H315 — Causes skin irritation and H318 — Causes serious eye damage. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
499-76-3
Jingsj CID
J-900114-3
Molecular Formula
C8H8O3
Molecular Weight
152.147 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point173-177 °C
Boiling Point331.3±30.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point168.4±21.1 °C
Exact Mass152.047348
PSA57.53000
LogP1.88
Vapor Pressure0.0±0.8 mmHg at 25°C
Refractive Index1.600

GHS Safety & Compliance

Corrosion / IrritantSignal word: Danger
  • H302 — Harmful if swallowed
  • H315 — Causes skin irritation
  • H318 — Causes serious eye damage
  • H335 — May cause respiratory irritation

Activity & Biological Data

TargetHuman Endogenous Metabolite
Additional Information[1]. Chapman PJ, et al. The bacterial metabolism of 2,4-xylenol. Biochem J. 1968 Dec;110(3):491-8.

Customs & Trade Information

HS Code2918290000
SummaryHS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 4-Hydroxy-3-methylbenzoic acid?

The CAS number of 4-Hydroxy-3-methylbenzoic acid is 499-76-3.

What are the molecular formula and molecular weight of 4-Hydroxy-3-methylbenzoic acid?

4-Hydroxy-3-methylbenzoic acid has molecular formula C8H8O3 and molecular weight 152.147 g/mol.

Is 4-Hydroxy-3-methylbenzoic acid hazardous?

4-Hydroxy-3-methylbenzoic acid has GHS signal word Danger and hazard statements H302 — Harmful if swallowed; H315 — Causes skin irritation; H318 — Causes serious eye damage.

What are the upstream and downstream products of 4-Hydroxy-3-methylbenzoic acid?

For 4-Hydroxy-3-methylbenzoic acid, Upstream Products: Carbon tetrachloride, o-Cresol, 4-Methoxy-3-methylbenzoic acid; Downstream Products: Methyl 4-hydroxy-3-methylbenzoate, methyl 4-methoxy-3-methylbenzoate, 2-Bromo-6-methylphenol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "4-Hydroxy-3-methylbenzoic acid (CAS 499-76-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-900114-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.