Gossypin

Also known as: ,7-trihydroxy-, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-8-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one, 2-(3,4-dihydroxyphenyl)-8-(beta-d-glucopyranosyloxy)-3,5,7-trihydroxy-4h-1-b, 3,3',4',5,7,8-HEXAHYDROXYFLAVONE 8-GLUCOSIDE, 3,3',4',5,7-PENTAHYDROXY-8-O-GLUCOSYLFLAVONE, 3,3',4',5,7-pentahydroxyflavone-8-O-glucoside, 3,5,7,8,3',4'-hexahydroxyflavone-8-O-glucopyranoside, 4h-1-benzopyran-4-one,2-(3,4-dihydroxyphenyl)-8-(beta-d-glucopyranosyloxy)-3,5, COTTON CELLULOSE, GOSSYPIN, Gossypetin 8-O-glucoside, Gossypetin-8-glucoside, gossypin, gossypin from hibiscus vitifolius*flowers

Gossypin (CAS 652-78-8) is a compound in the Alcohols category listed in the Jingsj chemical database. It has the molecular formula C21H20O13 and a molecular weight of 480.37600 g/mol. Key properties include a melting point of 229-230ºC, a boiling point of 886ºC at 760 mmHg, a density of 1.883 g/cm3 and a flash point of 310.8ºC. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 652-78-8
Jingsj CID: J-89938-7
Molecular Formula: C₂₁H₂₀O₁₃
Molecular Weight: 480.37600 g/mol
Category: Alcohols
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	229-230ºC
Boiling Point	886ºC at 760 mmHg
Density	1.883 g/cm3
Flash Point	310.8ºC
Exact Mass	480.09000
PSA	230.74000
Refractive Index	1.799

GHS Safety & Compliance

IrritantSignal word: Warning

H315 — Causes skin irritation
H319 — Causes serious eye irritation
H335 — May cause respiratory irritation

Activity & Biological Data

Target	IC50: NF-κB[1]
Additional Information	[1]. Ajaikumar B Kunnumakkara, et al. Gossypin, a pentahydroxy glucosyl flavone, inhibits the transforming growth factor beta-activated kinase-1-mediated NF-kappaB activation pathway, leading to potentiation of apoptosis, suppression of invasion, and abrogation of osteoclastogenesis. Blood. 2007 Jun 15;109(12):5112-21. [2]. Kanika Patel, et al. Gossypin: A phytochemical of multispectrum potential. the Journal of Coastal Life Medicine.

Target

IC50: NF-κB[1]

Additional Information

[1]. Ajaikumar B Kunnumakkara, et al. Gossypin, a pentahydroxy glucosyl flavone, inhibits the transforming growth factor beta-activated kinase-1-mediated NF-kappaB activation pathway, leading to potentiation of apoptosis, suppression of invasion, and abrogation of osteoclastogenesis. Blood. 2007 Jun 15;109(12):5112-21. [2]. Kanika Patel, et al. Gossypin: A phytochemical of multispectrum potential. the Journal of Coastal Life Medicine.

Frequently Asked Questions

What is the CAS number of Gossypin?

The CAS number of Gossypin is 652-78-8.

What are the molecular formula and molecular weight of Gossypin?

Gossypin has molecular formula C21H20O13 and molecular weight 480.37600 g/mol.

Is Gossypin hazardous?

Gossypin has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Gossypin (CAS 652-78-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-89938-7 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.