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Ciproxifan

Also known as: CS-757, Ciproxifan (FUB-359), Ciproxifan USP/EP/BP, Ciproxifan, >=99%, Cyclopropyl[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone, Cyclopropylpyrrol4-[3-(1H-imidazol-4-yl)propoxy] phenylmorphomethanone, Cyclopropyl{4-[3-(1H-imidazol-4-yl)propoxy]phenyl}methanone, FUB 359, FUB-359, Methanone, cyclopropyl[4-[3-(1H-iMidazol-4-yl)propoxy]phenyl]-, Methanone, cyclopropyl[4-[3-(1H-imidazol-4-yl)propoxy]phenyl]-, Methanone, cyclopropyl[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]-, cyclopropyl 4-(3-(1H-imidazol-4-yl)propyloxy)phenyl ketone, cyclopropyl 4-(3-(1H-imidazol-4-yl)propyloxy)phenyl methanone, cyclopropyl-[4-[3-(1H-imidazol-5-yl)propoxy]phenyl]methanone

Ciproxifan (CAS 184025-18-1) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C16H18N2O2 and a molecular weight of 270.326 g/mol. Key properties include a boiling point of 526.9±35.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 272.5±25.9 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
184025-18-1
Jingsj CID
J-89829-3
Molecular Formula
C16H18N2O2
Molecular Weight
270.326 g/mol
Category
Organic Compounds
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point526.9±35.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point272.5±25.9 °C
Exact Mass270.136841
PSA54.98000
LogP2.29
Appearancesolid | white
Vapor Pressure0.0±1.4 mmHg at 25°C
Refractive Index1.613
Storage Conditions-20℃
Additional PropertyH2O: insoluble

Activity & Biological Data

Additional Information[1]. Motawaj M, Arrang JM. Ciproxifan, a histamine H?-receptor antagonist?/?inverse agonist, modulates methamphetamine-induced sensitization in mice. Eur J Neurosci. 2011 Apr;33(7):1197-204. doi: 10.1111/j.1460-9568.2011.07618.x. [2]. Bardgett ME, et al. Ciproxifan, an H3 receptor antagonist, alleviates hyperactivity and cognitive deficits in the APP Tg2576 mouse model of Alzheimer's disease. Neurobiol Learn Mem. 2011 Jan;95(1):64-72. [3]. Bardgett ME, et al. The H3 antagonist, ciproxifan, alleviates the memory impairment but enhances the motor effects of MK-801 (dizocilpine) in rats. Neuropharmacology. 2010 Nov;59(6):492-502. [4]. Day M, et al. Differential effects of ciproxifan and nicotine on impulsivity and attention measures in the 5-choice serial reaction time test. Biochem Pharmacol. 2007 Apr 15;73(8):1123-34. [5]. Pillot C, et al. Ciproxifan, a histamine H3-receptor antagonist/inverse agonist, modulates the effects of methamphetamine on neuropeptide mRNA expression in rat striatum. Eur J Neurosci. 2003 Jan;17(2):307-14.

Frequently Asked Questions

What is the CAS number of Ciproxifan?

The CAS number of Ciproxifan is 184025-18-1.

What are the molecular formula and molecular weight of Ciproxifan?

Ciproxifan has molecular formula C16H18N2O2 and molecular weight 270.326 g/mol.

What are the upstream and downstream products of Ciproxifan?

For Ciproxifan, Upstream Products: 1H-Imidazole-4-propanol, 1-(triphenylmethyl)-, Cyclopropyl(4-hydroxyphenyl)methanone, Cyclopropyl 4-fluorophenyl ketone.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Ciproxifan (CAS 184025-18-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-89829-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.