(R)-(-)-Rolipram

Also known as: (-)-rolipram, (4R)-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one, (4R)-4-(3-(Cyclopentyloxy)-4-methoxyphenyl)pyrrolidine-2-one, (4R)-4-(3-cyclopentyloxy-4-methoxyphenyl)pyrrolidin-2-one, (4R)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE, (4R)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone, (4R)-4-[3-(Cyclopentyloxy)-4-methoxyphenyl]pyrrolidin-2-one, (4S)-4-[3-(CYCLOPENTYLOXY)-4-METHOXYPHENYL]PYRROLIDIN-2-ONE, (R)-(-)-ROLIPRAM, (R)-4-(3-(cyclopentyloxy)-4-methoxyphenyl)pyrrolidin-2-one, (S)-(+)-ROLIPRAM, (S)-ROLIPRAM, 2-Pyrrolidinone, 4-(3-(cyclopentyloxy)-4-methoxyphenyl)-, (R)-, 2-Pyrrolidinone, 4-[3-(cyclopentyloxy)-4-methoxyphenyl]-, (4R)-, R-(-)-4-[3-(cyclopentyloxy)-4-methoxyphenyl]-2-pyrrolidinone, Rolipram (R)-(-)-

(R)-(-)-Rolipram (CAS 85416-75-7) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C16H21NO3 and a molecular weight of 275.343 g/mol. Key properties include a melting point of 134 °C, a boiling point of 472.7±45.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 239.7±28.7 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 85416-75-7
Jingsj CID: J-89724-5
Molecular Formula: C₁₆H₂₁NO₃
Molecular Weight: 275.343 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	134 °C
Boiling Point	472.7±45.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	239.7±28.7 °C
Exact Mass	275.152130
PSA	47.56000
LogP	1.43
Vapor Pressure	0.0±1.2 mmHg at 25°C
Refractive Index	1.552

Activity & Biological Data

Additional Information	[1]. Guo C, et al. Bile Acids Control Inflammation and Metabolic Disorder through Inhibition of NLRP3 Inflammasome. Immunity. 2016 Oct 18;45(4):944.

Customs & Trade Information

HS Code	2933790090
Summary	2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of (R)-(-)-Rolipram?

The CAS number of (R)-(-)-Rolipram is 85416-75-7.

What are the molecular formula and molecular weight of (R)-(-)-Rolipram?

(R)-(-)-Rolipram has molecular formula C16H21NO3 and molecular weight 275.343 g/mol.

What are the upstream and downstream products of (R)-(-)-Rolipram?

For (R)-(-)-Rolipram, Upstream Products: 3-(Cyclopentyloxy)-4-methoxybenzaldehyde, Isovanillin, Cyclopentyl bromide.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "(R)-(-)-Rolipram (CAS 85416-75-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-89724-5 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.