Galantamine hydrobromide

Also known as: Galanthamine hydrobromide, Galantamine HBr, Galanthamine HBr, (-)-Galanthaminium bromide, (4aS,6R,8aS)-3-methoxy-11-methyl-5,6,9,10,11,12-hexahydro-4aH-[1]benzofuro[3a,3,2-ef][2]benzazepin-6-ol hydrobromide, Nivalin, Lycoremine

Galantamine hydrobromide (CAS 1953-04-4) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C17H22BrNO3 and a molecular weight of 368.266 g/mol. Key property: a melting point of 256 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 1953-04-4
Jingsj CID: J-8869-7
Molecular Formula: C₁₇H₂₂BrNO₃
Molecular Weight: 368.266 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	256 °C
Exact Mass	367.078308
PSA	41.93000
LogP	2.74630
Vapor Pressure	0mmHg at 25°C
Refractive Index	-95 ° (C=1.4, H2O)

GHS Safety & Compliance

Acute ToxicitySignal word: Danger

H301 — Toxic if swallowed

Activity & Biological Data

Additional Information	[1]. Kita Y, Ago Y, Takano E, Fukada A, Takuma K, Matsuda T.Galantamine increases hippocampal insulin-like growth factor 2 expression via α7 nicotinic acetylcholine receptors in mice.Psychopharmacology (Berl). 2012 Aug 30. [2]. Berkov S, Viladomat F, Codina C, Suárez S, Ravelo A, Bastida J.GC-MS of amaryllidaceous galanthamine-type alkaloids.J Mass Spectrom. 2012 Aug;47(8):1065-73. [3]. Park CW, Son DD, Kim JY, Oh TO, Ha JM, Rhee YS, Park ES.Investigation of formulation factors affecting in vitro and in vivo characteristics of a galantamine transdermal system.Int J Pharm. 2012 Oct 15;436(1-2):32-40. Epub 2012 Jul 5. [4]. Park YS, Kim SH, Kim SY, Kim YH, Lee MH, Yang SC, Shaw LM, Kang JS.Quantification of Galantamine in Human Plasma by Validated Liquid Chromatography-Tandem Mass Spectrometry using Glimepride as an Internal Standard: Application to Bioavailability Studies in 32 Healthy Korean Subjects.J Chromatogr Sci. 2012 Jun 28. [5]. Arias et al Galantamine prevents apoptosis induced by b-amyloid and thapsigargin: involvement of nicotinic acetycholine receptors. Neuropharmacology (2004) 46 103.

Additional Information

[1]. Kita Y, Ago Y, Takano E, Fukada A, Takuma K, Matsuda T.Galantamine increases hippocampal insulin-like growth factor 2 expression via α7 nicotinic acetylcholine receptors in mice.Psychopharmacology (Berl). 2012 Aug 30. [2]. Berkov S, Viladomat F, Codina C, Suárez S, Ravelo A, Bastida J.GC-MS of amaryllidaceous galanthamine-type alkaloids.J Mass Spectrom. 2012 Aug;47(8):1065-73. [3]. Park CW, Son DD, Kim JY, Oh TO, Ha JM, Rhee YS, Park ES.Investigation of formulation factors affecting in vitro and in vivo characteristics of a galantamine transdermal system.Int J Pharm. 2012 Oct 15;436(1-2):32-40. Epub 2012 Jul 5. [4]. Park YS, Kim SH, Kim SY, Kim YH, Lee MH, Yang SC, Shaw LM, Kang JS.Quantification of Galantamine in Human Plasma by Validated Liquid Chromatography-Tandem Mass Spectrometry using Glimepride as an Internal Standard: Application to Bioavailability Studies in 32 Healthy Korean Subjects.J Chromatogr Sci. 2012 Jun 28. [5]. Arias et al Galantamine prevents apoptosis induced by b-amyloid and thapsigargin: involvement of nicotinic acetycholine receptors. Neuropharmacology (2004) 46 103.

Frequently Asked Questions

What is the CAS number of Galantamine hydrobromide?

The CAS number of Galantamine hydrobromide is 1953-04-4.

What are the molecular formula and molecular weight of Galantamine hydrobromide?

Galantamine hydrobromide has molecular formula C17H22BrNO3 and molecular weight 368.266 g/mol.

Is Galantamine hydrobromide hazardous?

Galantamine hydrobromide has GHS signal word Danger and hazard statements H301 — Toxic if swallowed.

What are the upstream and downstream products of Galantamine hydrobromide?

For Galantamine hydrobromide, Upstream Products: Galanthaminone, Galanthamine, N-(4-Hydroxyphenethyl)-N-(2-bromo-5-hydroxy-4-methoxybenzyl)formamide; Downstream Products: N-Desmethylgalanthamine, Galanthamine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Galantamine hydrobromide (CAS 1953-04-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-8869-7 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.