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Dimethyl malonate

Also known as: Dimethyl propanedioate, Methyl malonate, Malonic acid dimethyl ester, Propanedioic acid dimethyl ester, dimethyl propanedioate, dimethyl malonate

Dimethyl malonate (CAS 108-59-8) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C5H8O4 and a molecular weight of 132.115 g/mol. Key properties include a melting point of −62 °C(lit.), a boiling point of 177.1±8.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 90.0±0.0 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
108-59-8
Jingsj CID
J-8858-4
Molecular Formula
C5H8O4
Molecular Weight
132.115 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point−62 °C(lit.)
Boiling Point177.1±8.0 °C at 760 mmHg
Density1.1±0.1 g/cm3
Flash Point90.0±0.0 °C
Exact Mass132.042252
PSA52.60000
LogP-0.36
Additional Property>1 (vs air)
Vapor Pressure1.1±0.3 mmHg at 25°C
Refractive Index1.402
Additional Propertynegligible

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

Additional Information[1]. Xu J, et al. Inhibiting Succinate Dehydrogenase by Dimethyl Malonate Alleviates Brain Damage in a Rat Model of Cardiac Arrest. Neuroscience. 2018 Nov 21;393:24-32.

Customs & Trade Information

HS Code2917190090
Summary2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Dimethyl malonate?

The CAS number of Dimethyl malonate is 108-59-8.

What are the molecular formula and molecular weight of Dimethyl malonate?

Dimethyl malonate has molecular formula C5H8O4 and molecular weight 132.115 g/mol.

Is Dimethyl malonate hazardous?

Dimethyl malonate has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of Dimethyl malonate?

For Dimethyl malonate, Upstream Products: Methyl chloroacetate, Methanol, Malonic acid; Downstream Products: Dimethyl 2-allyl-2-(prop-2-yn-1-yl)malonate, 1,1,2,2-Ethanetetracarboxylic acid, tetramethyl ester.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Dimethyl malonate (CAS 108-59-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-8858-4 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.