Cytarabine hydrochloride

Also known as: 1-β-D-Arabinofuranosylcytosine hydrochloride, Cytosine arabinoside hydrochloride, Ara-C hydrochloride, 4-Amino-1-β-D-arabinofuranosyl-2(1H)-pyrimidinone hydrochloride, Cytarabine HCl, 1-beta-D-Arabinofuranosylcytosine hydrochloride, Arabinosylcytosine hydrochloride, 1-β-D-Arabinofuranosyl-4-amino-2(1H)-pyrimidinone hydrochloride, U 19920A

Cytarabine hydrochloride (CAS 69-74-9) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C9H14ClN3O5 and a molecular weight of 279.68 g/mol. Key properties include a melting point of 197-198 °C(lit.), a boiling point of 545.7ºC at 760 mmHg and a flash point of 283.8ºC. It is classified under GHS with signal word Warning and hazard statements H317 — May cause an allergic skin reaction, H319 — Causes serious eye irritation and H341 — Suspected of causing genetic defects. It is listed by 1 supplier, from 5.04 to 5.60 CNY. Record last updated Aug 21, 2026.

CAS No.: 69-74-9
Jingsj CID: J-885065-2
Molecular Formula: C₉H₁₄ClN₃O₅
Molecular Weight: 279.68 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Supplier	Purity / Pack	Base Price	Unit Price	Origin
Maikuo Made to Order	97% 500g	¥2,520.00	$0.75 /gBest ¥5.04/g CNY	CN China MOQ 500g	View Product
Maikuo Made to Order	97% 100g	¥530.00	$0.79 /g ¥5.30/g CNY	CN China MOQ 100g	View Product
Maikuo Made to Order	97% 25g	¥140.00	$0.84 /g ¥5.60/g CNY	CN China MOQ 25g	View Product

Physicochemical Properties

Melting Point	197-198 °C(lit.)
Boiling Point	545.7ºC at 760 mmHg
Flash Point	283.8ºC
Exact Mass	279.062195
PSA	130.83000
SMILES	C1=CN(C(=O)N=C1N)[C@H]2[C@H]([C@@H]([C@H](O2)CO)O)O.Cl
InChIKey	KCURWTAZOZXKSJ-JBMRGDGGSA-N
InChI	1S/C9H13N3O5.ClH/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8;/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16);1H/t4-,6-,7+,8-;/m1./s1

GHS Safety & Compliance

Irritant / Health HazardSignal word: Warning

H317 — May cause an allergic skin reaction
H319 — Causes serious eye irritation
H341 — Suspected of causing genetic defects
H361 — Suspected of damaging fertility or the unborn child

Activity & Biological Data

Target	IC50: 16 nM (DNA synthesis)
Additional Information	[1]. Tobias, S.C. and R.F. Borch, Synthesis and biological evaluation of a cytarabine phosphoramidate prodrug. Mol Pharm, 2004. 1(2): p. 112-6. [2]. Besirli, C.G., et al. Cytosine arabinoside rapidly activates Bax-dependent apoptosis and a delayed Bax-independent death pathway in sympathetic neurons. Cell Death Differ, 2003. 10(9): p. 1045-58. [3]. Yamauchi, H., et al., Involvement of p53 in 1-beta-D-arabinofuranosylcytosine-induced trophoblastic cell apoptosis and impaired proliferation in rat placenta. Biol Reprod, 2004. 70(6): p. 1762-7. [4]. Richel, D.J., et al., Comparison of the antileukaemic activity of 5 aza-2-deoxycytidine and arabinofuranosyl-cytosine in rats with myelocytic leukaemia. Br J Cancer, 1988. 58(6): p. 730-3.

Target

IC50: 16 nM (DNA synthesis)

Additional Information

[1]. Tobias, S.C. and R.F. Borch, Synthesis and biological evaluation of a cytarabine phosphoramidate prodrug. Mol Pharm, 2004. 1(2): p. 112-6. [2]. Besirli, C.G., et al. Cytosine arabinoside rapidly activates Bax-dependent apoptosis and a delayed Bax-independent death pathway in sympathetic neurons. Cell Death Differ, 2003. 10(9): p. 1045-58. [3]. Yamauchi, H., et al., Involvement of p53 in 1-beta-D-arabinofuranosylcytosine-induced trophoblastic cell apoptosis and impaired proliferation in rat placenta. Biol Reprod, 2004. 70(6): p. 1762-7. [4]. Richel, D.J., et al., Comparison of the antileukaemic activity of 5 aza-2-deoxycytidine and arabinofuranosyl-cytosine in rats with myelocytic leukaemia. Br J Cancer, 1988. 58(6): p. 730-3.

Customs & Trade Information

HS Code	2942000000

Frequently Asked Questions

What is the CAS number of Cytarabine hydrochloride?

The CAS number of Cytarabine hydrochloride is 69-74-9.

What are the molecular formula and molecular weight of Cytarabine hydrochloride?

Cytarabine hydrochloride has molecular formula C9H14ClN3O5 and molecular weight 279.68 g/mol.

Which suppliers offer Cytarabine hydrochloride?

1 supplier(s) listed; reference unit price ¥5.04–5.60 /g.

Is Cytarabine hydrochloride hazardous?

Cytarabine hydrochloride has GHS signal word Warning and hazard statements H317 — May cause an allergic skin reaction; H319 — Causes serious eye irritation; H341 — Suspected of causing genetic defects.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Cytarabine hydrochloride (CAS 69-74-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-885065-2 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.