8-Hydroxyguanine

Also known as: 2-Amino-6,8-dihydroxypurine, 2-Amino-6,8-purinediol, 8-Oxoguanine, 7,8-Dihydro-8-oxoguanine, 8-Oxo-7,8-dihydroguanine, 8-OH-Gua, 8-Oxodihydroguanine, NSC 22720

8-Hydroxyguanine (CAS 5614-64-2) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C5H5N5O2 and a molecular weight of 167.12500 g/mol. Key properties include a melting point of >400ºC dec., a boiling point of 327.7ºC at 760 mmHg, a density of 2.49g/cm3 and a flash point of 152ºC. No supplier offers are currently listed; request a quote. Record last updated Nov 3, 2026.

CAS No.: 5614-64-2
Jingsj CID: J-853890-7
Molecular Formula: C₅H₅N₅O₂
Molecular Weight: 167.12500 g/mol
Category: Pharma Intermediates
Last updated: 11/3/2026

Request MSDS / TDS

No offers for this compound yet.

Request a quote

Physicochemical Properties

Melting Point	>400ºC dec.
Boiling Point	327.7ºC at 760 mmHg
Density	2.49g/cm3
Flash Point	152ºC
Exact Mass	167.04400
PSA	120.94000
Refractive Index	2.156

Activity & Biological Data

Target	Human Endogenous Metabolite
Additional Information	[1]. Arai T, et al. High accumulation of oxidative DNA damage, 8-hydroxyguanine, in Mmh/Ogg1 deficient mice by chronic oxidative stress. Carcinogenesis. 2002 Dec;23(12):2005-10. [2]. Floyd RA, et al. The role of 8-hydroxyguanine in carcinogenesis. Carcinogenesis. 1990 Sep;11(9):1447-50. [3]. Cheng KC, et al. 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G----T and A----C substitutions. J Biol Chem. 1992 Jan 5;267(1):166-72.

Target

Human Endogenous Metabolite

Additional Information

[1]. Arai T, et al. High accumulation of oxidative DNA damage, 8-hydroxyguanine, in Mmh/Ogg1 deficient mice by chronic oxidative stress. Carcinogenesis. 2002 Dec;23(12):2005-10. [2]. Floyd RA, et al. The role of 8-hydroxyguanine in carcinogenesis. Carcinogenesis. 1990 Sep;11(9):1447-50. [3]. Cheng KC, et al. 8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G----T and A----C substitutions. J Biol Chem. 1992 Jan 5;267(1):166-72.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 8-Hydroxyguanine?

The CAS number of 8-Hydroxyguanine is 5614-64-2.

What are the molecular formula and molecular weight of 8-Hydroxyguanine?

8-Hydroxyguanine has molecular formula C5H5N5O2 and molecular weight 167.12500 g/mol.

What are the upstream and downstream products of 8-Hydroxyguanine?

For 8-Hydroxyguanine, Upstream Products: Guanine; Downstream Products: 8-Hydroxyguanosine, Uric Acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 11/3/2026

How to cite: Jingsj. "8-Hydroxyguanine (CAS 5614-64-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-853890-7 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.