(S)-Thalidomide
Also known as: (-)-Thalidomide, (S)-(-)-Thalidomide, L-Thalidomide, (-)-N-[(S)-2,6-Dioxo-3-piperidinyl]phthalimide, (3S)-3-(1,3-Dioxo-2H-isoindole-2-yl)piperidine-2,6-dione, (S)-2-(2,6-Dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
(S)-Thalidomide (CAS 841-67-8) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C13H10N2O4 and a molecular weight of 258.22900 g/mol. Key properties include a melting point of 269-271ºC, a boiling point of 509.7ºC at 760 mmHg, a density of 1.503g/cm3 and a flash point of 262.1ºC. It is classified under GHS with signal word Danger and hazard statements H302 — Harmful if swallowed and H360 — May damage fertility or the unborn child. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 841-67-8
- Jingsj CID
- J-828754-5
- Molecular Formula
- C13H10N2O4
- Molecular Weight
- 258.22900 g/mol
- Category
- Organic Bases
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 269-271ºC |
|---|---|
| Boiling Point | 509.7ºC at 760 mmHg |
| Density | 1.503g/cm3 |
| Flash Point | 262.1ºC |
| Exact Mass | 258.06400 |
| PSA | 83.55000 |
| LogP | 0.35450 |
| Refractive Index | 1.646 |
GHS Safety & Compliance
- H302 — Harmful if swallowed
- H360 — May damage fertility or the unborn child
Activity & Biological Data
| Target | Apoptosis[1] |
|---|---|
| Additional Information | [1]. Liu WM, et al. s-thalidomide has a greater effect on apoptosis than angiogenesis in a multiple myeloma cell line. Hematol J. 2004;5(3):247-54. [2]. Stephens TD. The effect of thalidomide in chicken embryos. Birth Defects Res A Clin Mol Teratol. 2009 Aug;85(8):725-31. [3]. Murphy S, et al. Enantioselectivity of thalidomide serum and tissue concentrations in a rat glioma model and effects of combination treatment with cisplatin and BCNU. J Pharm Pharmacol. 2007 Jan;59(1):105-14. [4]. Tokunaga E, et al. Understanding the Thalidomide Chirality in Biological Processes by the Self-disproportionation of Enantiomers. Sci Rep. 2018 Nov 20;8(1):17131. |
Customs & Trade Information
| HS Code | 2925190090 |
|---|---|
| Summary | 2925190090 other imides and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of (S)-Thalidomide?
The CAS number of (S)-Thalidomide is 841-67-8.
What are the molecular formula and molecular weight of (S)-Thalidomide?
(S)-Thalidomide has molecular formula C13H10N2O4 and molecular weight 258.22900 g/mol.
Is (S)-Thalidomide hazardous?
(S)-Thalidomide has GHS signal word Danger and hazard statements H302 — Harmful if swallowed; H360 — May damage fertility or the unborn child.
What are the upstream and downstream products of (S)-Thalidomide?
For (S)-Thalidomide, Upstream Products: N-ALPHA-PHTHALYL-L-GLUTAMINE, Thalidomide, Phthalic anhydride; Downstream Products: (R)-(+)-Thalidomide.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "(S)-Thalidomide (CAS 841-67-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-828754-5 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.