Ketoprofen
Also known as: 2-(3-Benzoylphenyl)propanoic acid, 2-(3-Benzoylphenyl)propionic acid, 3-Benzoylhydratropic acid, alpha-Methyl-3-benzoylphenylacetic acid, ORUDIS, ORUVAIL, Profenid, RP 19583, RU 4733, Ketoprofene, Ketoprophene, Racemic Ketoprofen, MFCD00055790
Ketoprofen (CAS 22071-15-4) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C16H14O3 and a molecular weight of 254.281 g/mol. Key properties include a melting point of 93-96°C, a boiling point of 431.3±28.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 228.8±20.5 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 22071-15-4
- Jingsj CID
- J-8263-3
- Molecular Formula
- C16H14O3
- Molecular Weight
- 254.281 g/mol
- Category
- Ketones
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 93-96°C |
|---|---|
| Boiling Point | 431.3±28.0 °C at 760 mmHg |
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 228.8±20.5 °C |
| Exact Mass | 254.094299 |
| PSA | 54.37000 |
| LogP | 2.81 |
| Vapor Pressure | 0.0±1.1 mmHg at 25°C |
| Refractive Index | 1.592 |
GHS Safety & Compliance
- H301 — Toxic if swallowed
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Target | COX-1:2 nM (IC50, in human blood monocytes) COX-2:26 nM (IC50, in human blood monocytes) |
|---|---|
| Additional Information | [1]. Palomer A, et al. Structure-based design of cyclooxygenase-2 selectivity into ketoprofen. Bioorg Med Chem Lett. 2002 Feb 25;12(4):533-7. [2]. Negus SS, et al. Effects of ketoprofen, morphine, and kappa opioids on pain-related depression of nesting in mice. Pain. 2015 Jun;156(6):1153-60. |
Customs & Trade Information
| HS Code | 2918300090 |
|---|---|
| Summary | 2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of Ketoprofen?
The CAS number of Ketoprofen is 22071-15-4.
What are the molecular formula and molecular weight of Ketoprofen?
Ketoprofen has molecular formula C16H14O3 and molecular weight 254.281 g/mol.
Is Ketoprofen hazardous?
Ketoprofen has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H315 — Causes skin irritation; H319 — Causes serious eye irritation.
What are the upstream and downstream products of Ketoprofen?
For Ketoprofen, Upstream Products: 3-Pentanone, 2-(3-Benzoylphenyl)propionitrile; Downstream Products: 3-Acetylbenzoic acid, 3-Benzoylbenzoic acid, Dexketoprofen.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Ketoprofen (CAS 22071-15-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-8263-3 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.