![Molecular structure of 6-Cyano-N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-1-(1-ethylpropyl)-1H-indole-4-carboxamide (CAS 1418308-27-6)](/images/chem_structures_svg/358/1418308-27-6.svg)
6-Cyano-N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-1-(1-ethylpropyl)-1H-indole-4-carboxamide
Also known as: EI1, EI-1, EI 1, 6-Cyano-N-[(4,6-dimethyl-2-oxo-1,2-dihydro-3-pyridinyl)methyl]-1-(3-pentanyl)-1H-indole-4-carboxamide, 6-cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide, CS-2378, EZH2 inhibitor EI1
6-Cyano-N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-1-(1-ethylpropyl)-1H-indole-4-carboxamide (CAS 1418308-27-6) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C23H26N4O2 and a molecular weight of 390.478 g/mol. Key properties include a boiling point of 675.9±55.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 362.6±31.5 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 1418308-27-6
- Jingsj CID
- J-811500-5
- Molecular Formula
- C23H26N4O2
- Molecular Weight
- 390.478 g/mol
- Category
- Pharma Intermediates
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Boiling Point | 675.9±55.0 °C at 760 mmHg |
|---|---|
| Density | 1.2±0.1 g/cm3 |
| Flash Point | 362.6±31.5 °C |
| Exact Mass | 390.205566 |
| PSA | 94.43000 |
| LogP | 2.92 |
| Vapor Pressure | 0.0±2.1 mmHg at 25°C |
| Refractive Index | 1.617 |
| Storage Conditions | -20℃ |
Activity & Biological Data
| Target | IC50: 15 nM (EZH2 wild type), 13 nM (EZH2 Y641F mutant type) |
|---|---|
| Additional Information | [1]. Qi W, et al. Selective inhibition of Ezh2 by a small molecule inhibitor blocks tumor cells proliferation. Proc Natl Acad Sci U S A. 2012 Dec 26;109(52):21360-5. |
Frequently Asked Questions
What is the CAS number of 6-Cyano-N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-1-(1-ethylpropyl)-1H-indole-4-carboxamide?
The CAS number of 6-Cyano-N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-1-(1-ethylpropyl)-1H-indole-4-carboxamide is 1418308-27-6.
What are the molecular formula and molecular weight of 6-Cyano-N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-1-(1-ethylpropyl)-1H-indole-4-carboxamide?
6-Cyano-N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-1-(1-ethylpropyl)-1H-indole-4-carboxamide has molecular formula C23H26N4O2 and molecular weight 390.478 g/mol.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "6-Cyano-N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-1-(1-ethylpropyl)-1H-indole-4-carboxamide (CAS 1418308-27-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-811500-5 (accessed 2026-11-07).
Data for reference only; verify product details with suppliers before purchase.