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Esflurbiprofen

Also known as: (S)-Flurbiprofen, (S)-(+)-2-Fluoro-alpha-methyl-4-biphenylacetic acid, (S)-2-(2-fluorobiphenyl-4-yl)propanoic acid, (S)-(+)-Flurbiprofen, Esflurbiprofene, Esflurbiprofeno, Esflurbiprofenum, UNII-J5ZZK9P7MX

Esflurbiprofen (CAS 51543-39-6) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C15H13FO2 and a molecular weight of 244.261 g/mol. Key properties include a melting point of 109-110ºC(lit.), a boiling point of 376.2±30.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 181.3±24.6 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
51543-39-6
Jingsj CID
J-7757-6
Molecular Formula
C15H13FO2
Molecular Weight
244.261 g/mol
Category
Organohalogen Compounds
Last updated
8/21/2026

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Physicochemical Properties

Melting Point109-110ºC(lit.)
Boiling Point376.2±30.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point181.3±24.6 °C
Exact Mass244.089951
PSA37.30000
LogP4.11
Vapor Pressure0.0±0.9 mmHg at 25°C
Refractive Index1.568

Activity & Biological Data

TargetCOX-1:0.48 μM (IC50) COX-2:0.47 μM (IC50)
Additional Information[1]. A Carabaza, et al. Stereoselective Inhibition of Inducible Cyclooxygenase by Chiral Nonsteroidal Antiinflammatory Drugs. J Clin Pharmacol. 1996 Jun;36(6):505-12. [2]. B Averbeck, et al. Inflammatory Mediators Do Not Stimulate CGRP Release if Prostaglandin Synthesis Is Blocked by S(+)-flurbiprofen in Isolated Rat Skin. Inflamm Res. 2003 Dec;52(12):519-23.

Frequently Asked Questions

What is the CAS number of Esflurbiprofen?

The CAS number of Esflurbiprofen is 51543-39-6.

What are the molecular formula and molecular weight of Esflurbiprofen?

Esflurbiprofen has molecular formula C15H13FO2 and molecular weight 244.261 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Esflurbiprofen (CAS 51543-39-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-7757-6 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.