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Pamoic acid

Also known as: Embonic acid, 4,4'-Methylenebis(3-hydroxy-2-naphthoic acid), 1,1'-Methylene-bis(2-hydroxy-3-naphthoic acid), 2,2'-Dihydroxy-1,1'-dinaphthylmethane-3,3'-dicarboxylic acid, 4,4'-Methylenedi(3-hydroxy-2-naphthoic acid)

Pamoic acid (CAS 130-85-8) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C23H16O6 and a molecular weight of 388.38 g/mol. Key properties include a melting point of ≥300 °C (dec.), a boiling point of 642.7±55.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 356.5±28.0 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Nov 3, 2026.

CAS No.
130-85-8
Jingsj CID
J-6776-6
Molecular Formula
C23H16O6
Molecular Weight
388.38 g/mol
Category
Organic Acids
Last updated
11/3/2026

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Physicochemical Properties

Melting Point≥300 °C (dec.)
Boiling Point642.7±55.0 °C at 760 mmHg
Density1.5±0.1 g/cm3
Flash Point356.5±28.0 °C
Exact Mass388.094696
PSA115.06000
LogP6.35
Vapor Pressure0.0±2.0 mmHg at 25°C
Refractive Index1.782
Additional PropertyPRACTICALLY INSOLUBLE

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

TargetEC50: 79 nM (GPR35)[1]
Additional Information[1]. Ozayra Sharmin, et al. Activation of GPR35 protects against cerebral ischemia by recruiting monocyte-derived macrophages. Sci Rep. 2020 Jun 10;10(1):9400. [2]. Pingwei Zhao, et al. Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity. Mol Pharmacol. 2010 Oct;78(4):560-8.

Customs & Trade Information

HS Code2918290000
SummaryHS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Pamoic acid?

The CAS number of Pamoic acid is 130-85-8.

What are the molecular formula and molecular weight of Pamoic acid?

Pamoic acid has molecular formula C23H16O6 and molecular weight 388.38 g/mol.

Is Pamoic acid hazardous?

Pamoic acid has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of Pamoic acid?

For Pamoic acid, Upstream Products: Formaldehyde, 3-Hydroxy-2-naphthoic acid, acetic acid; Downstream Products: Pamoic acid disodium salt monohydrate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Pamoic acid (CAS 130-85-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-6776-6 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.