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2-Chloro-1,1,1-trimethoxyethane

Also known as: 1,1,1-Trimethoxy-2-chloroethane, Trimethyl chloro-orthoacetate, TMOCA, Ethane, 2-chloro-1,1,1-trimethoxy-, Aprepitant impurity 46, Fosaprepitant impurity 36, MFCD00216629

2-Chloro-1,1,1-trimethoxyethane (CAS 74974-54-2) is a compound in the Aliphatic Hydrocarbons category listed in the Jingsj chemical database. It has the molecular formula C5H11ClO3 and a molecular weight of 154.592 g/mol. Key properties include a boiling point of 143.2±35.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 40.8±26.0 °C. It is classified under GHS with signal word Warning and hazard statements H226 — Flammable liquid and vapour. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
74974-54-2
Jingsj CID
J-6638-3
Molecular Formula
C5H11ClO3
Molecular Weight
154.592 g/mol
Category
Aliphatic Hydrocarbons
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point143.2±35.0 °C at 760 mmHg
Density1.1±0.1 g/cm3
Flash Point40.8±26.0 °C
Exact Mass154.039673
PSA27.69000
LogP1.84
Vapor Pressure6.8±0.3 mmHg at 25°C
Refractive Index1.412

GHS Safety & Compliance

FlammableSignal word: Warning
  • H226 — Flammable liquid and vapour

Customs & Trade Information

HS Code2909199090
Summary2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 2-Chloro-1,1,1-trimethoxyethane?

The CAS number of 2-Chloro-1,1,1-trimethoxyethane is 74974-54-2.

What are the molecular formula and molecular weight of 2-Chloro-1,1,1-trimethoxyethane?

2-Chloro-1,1,1-trimethoxyethane has molecular formula C5H11ClO3 and molecular weight 154.592 g/mol.

Is 2-Chloro-1,1,1-trimethoxyethane hazardous?

2-Chloro-1,1,1-trimethoxyethane has GHS signal word Warning and hazard statements H226 — Flammable liquid and vapour.

What are the upstream and downstream products of 2-Chloro-1,1,1-trimethoxyethane?

For 2-Chloro-1,1,1-trimethoxyethane, Upstream Products: 1,1,1-Trimethoxyethane, Methyl chloroacetate, Trimethyl orthoformate; Downstream Products: 5-Chloro-2-(chloromethyl)-1,3-benzothiazole, Methyl 3-chloro-4-methoxybenzoate, 2-(Chloromethyl)-5-phenyl-1,3,4-oxadiazole.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "2-Chloro-1,1,1-trimethoxyethane (CAS 74974-54-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-6638-3 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.