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Tofisopam

Also known as: Grandaxin, Seriel, EGYT 341, 1-(3,4-Dimethoxyphenyl)-5-ethyl-7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepine, 7,8-Dimethoxy-1-(3,4-dimethoxyphenyl)-5-ethyl-4-methyl-5H-2,3-benzodiazepine, Tofisopamum, Tofizopam, Emandaxin, Nodeprine

Tofisopam (CAS 22345-47-7) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C22H26N2O4 and a molecular weight of 382.46000 g/mol. Key properties include a melting point of 155-159ºC, a boiling point of 479.0±45.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 195.2±21.2 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed and H400 — Very toxic to aquatic life. No supplier offers are currently listed; request a quote. Record last updated Nov 2, 2026.

CAS No.
22345-47-7
Jingsj CID
J-6508-7
Molecular Formula
C22H26N2O4
Molecular Weight
382.46000 g/mol
Category
Organic Compounds
Last updated
11/2/2026

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Physicochemical Properties

Melting Point155-159ºC
Boiling Point479.0±45.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point195.2±21.2 °C
Exact Mass565.226501
PSA61.64000
LogP2.39
Vapor Pressure0.0±1.2 mmHg at 25°C
Refractive Index1.558

GHS Safety & Compliance

Irritant / Environmental HazardSignal word: Warning
  • H302 — Harmful if swallowed
  • H400 — Very toxic to aquatic life

Activity & Biological Data

Additional Information[1]. Umut İrfan Üçel, et al. Antiamnesic effects of tofisopam against scopolamine-induced cognitive impairments in rats. Pharmacol Biochem Behav. 2020 Mar;190:172858.

Frequently Asked Questions

What is the CAS number of Tofisopam?

The CAS number of Tofisopam is 22345-47-7.

What are the molecular formula and molecular weight of Tofisopam?

Tofisopam has molecular formula C22H26N2O4 and molecular weight 382.46000 g/mol.

Is Tofisopam hazardous?

Tofisopam has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H400 — Very toxic to aquatic life.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Tofisopam (CAS 22345-47-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-6508-7 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.