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2-(Trifluoroacetyl)thiophene

Also known as: 2,2,2-Trifluoro-1-(2-thienyl)ethanone, 2-Thienyl trifluoromethyl ketone, 1-(Thien-2-yl)-2,2,2-trifluoroethan-1-one, 2,2,2-Trifluoro-1-thiophen-2-yl-ethanone, Ethanone, 2,2,2-trifluoro-1-(2-thienyl)-, MFCD00041427

2-(Trifluoroacetyl)thiophene (CAS 651-70-7) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C6H3F3OS and a molecular weight of 180.14800 g/mol. Key properties include a boiling point of 163ºC, a density of 1.403 and a flash point of 58.9 °C. It is classified under GHS with signal word Warning and hazard statements H226 — Flammable liquid and vapour, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Nov 2, 2026.

CAS No.
651-70-7
Jingsj CID
J-5684-8
Molecular Formula
C6H3F3OS
Molecular Weight
180.14800 g/mol
Category
Pharma Intermediates
Last updated
11/2/2026

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Physicochemical Properties

Boiling Point163ºC
Density1.403
Flash Point58.9 °C
Exact Mass179.98600
PSA45.31000
LogP2.49310
Refractive Indexn20/D 1.486(lit.)

GHS Safety & Compliance

Flammable / IrritantSignal word: Warning
  • H226 — Flammable liquid and vapour
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Customs & Trade Information

HS Code2934999090
Summary2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 2-(Trifluoroacetyl)thiophene?

The CAS number of 2-(Trifluoroacetyl)thiophene is 651-70-7.

What are the molecular formula and molecular weight of 2-(Trifluoroacetyl)thiophene?

2-(Trifluoroacetyl)thiophene has molecular formula C6H3F3OS and molecular weight 180.14800 g/mol.

Is 2-(Trifluoroacetyl)thiophene hazardous?

2-(Trifluoroacetyl)thiophene has GHS signal word Warning and hazard statements H226 — Flammable liquid and vapour; H315 — Causes skin irritation; H319 — Causes serious eye irritation.

What are the upstream and downstream products of 2-(Trifluoroacetyl)thiophene?

For 2-(Trifluoroacetyl)thiophene, Upstream Products: Ethyl trifluoroacetate, 2-Thienylmagnesium bromide, 2-Thiophenecarbonyl chloride; Downstream Products: 1,4-Di(2-thienyl)-1,4-butanedione.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "2-(Trifluoroacetyl)thiophene (CAS 651-70-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-5684-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.