AM095 free acid

Also known as: AM095, AM-095, AM 095, AM095 free base, AM-095 free acid, AM 095 free acid, [4'-[3-Methyl-4-[[[((R)-1-phenylethyl)oxy]carbonyl]amino]isoxazol-5-yl]biphenyl-4-yl]acetic acid, (R)-2-(4'-(3-methyl-4-((1-phenylethoxy)carbonylamino)isoxazol-5-yl)biphenyl-4-yl)acetic acid, 2-[4-[4-[3-methyl-4-[[(1R)-1-phenylethoxy]carbonylamino]-1,2-oxazol-5-yl]phenyl]phenyl]acetic acid, [1,1'-Biphenyl]-4-acetic acid, 4'-[3-methyl-4-[[[(1R)-1-phenylethoxy]carbonyl]amino]-5-isoxazolyl]-, CS-1129, CS-1624, HY-16040, KB-63701, CHEMBL2182052

AM095 free acid (CAS 1228690-36-5) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C27H24N2O5 and a molecular weight of 456.490 g/mol. Key properties include a boiling point of 641.9±55.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 342.0±31.5 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 1228690-36-5
Jingsj CID: J-54618-9
Molecular Formula: C₂₇H₂₄N₂O₅
Molecular Weight: 456.490 g/mol
Category: Organic Acids
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	641.9±55.0 °C at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	342.0±31.5 °C
Exact Mass	456.168518
PSA	105.15000
LogP	4.94
Vapor Pressure	0.0±2.0 mmHg at 25°C
Refractive Index	1.629
Storage Conditions	-20℃

Activity & Biological Data

Target	IC50: 0.98 μM (human LPA1), 0.73 μM (mouse LPA1)
Additional Information	[1]. Castelino FV, et al. Amelioration of dermal fibrosis by genetic deletion or pharmacologic antagonism of lysophosphatidic acid receptor 1 in a mouse model of scleroderma. Arthritis Rheum. 2011 May;63(5):1405-15. [2]. Ruisanchez E, et al. Lysophosphatidic acid induces vasodilation mediated by LPA1 receptors, phospholipase C, and endothelial nitric oxide synthase. FASEB J. 2014 Feb;28(2):880-90. [3]. Swaney, J. S., et al. Pharmacokinetic and pharmacodynamic characterization of an oral lysophosphatidic acid type 1 receptor-selective antagonist. Journal of Pharmacology and Experimental Therapeutics (2011), 336(3), 693-700.

Target

IC50: 0.98 μM (human LPA1), 0.73 μM (mouse LPA1)

Additional Information

[1]. Castelino FV, et al. Amelioration of dermal fibrosis by genetic deletion or pharmacologic antagonism of lysophosphatidic acid receptor 1 in a mouse model of scleroderma. Arthritis Rheum. 2011 May;63(5):1405-15. [2]. Ruisanchez E, et al. Lysophosphatidic acid induces vasodilation mediated by LPA1 receptors, phospholipase C, and endothelial nitric oxide synthase. FASEB J. 2014 Feb;28(2):880-90. [3]. Swaney, J. S., et al. Pharmacokinetic and pharmacodynamic characterization of an oral lysophosphatidic acid type 1 receptor-selective antagonist. Journal of Pharmacology and Experimental Therapeutics (2011), 336(3), 693-700.

Frequently Asked Questions

What is the CAS number of AM095 free acid?

The CAS number of AM095 free acid is 1228690-36-5.

What are the molecular formula and molecular weight of AM095 free acid?

AM095 free acid has molecular formula C27H24N2O5 and molecular weight 456.490 g/mol.

What are the upstream and downstream products of AM095 free acid?

For AM095 free acid, Upstream Products: Acetophenone, Ethyl 4-bromophenylacetate, (R)-(+)-1-Phenylethanol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "AM095 free acid (CAS 1228690-36-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-54618-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.