trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic acid

Also known as: C75, C75 trans, (±)-C75, racemic-C75, 4-Methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid, Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic acid, 3-Furancarboxylic acid, tetrahydro-4-methylene-2-octyl-5-oxo-, trans-, (2R*,3S*)-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic acid, UNII:8E9A8CTX2H

trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic acid (CAS 191282-48-1) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C14H22O4 and a molecular weight of 254.322 g/mol. Key properties include a boiling point of 432.1±45.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 159.2±22.2 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 191282-48-1
Jingsj CID: J-49772-9
Molecular Formula: C₁₄H₂₂O₄
Molecular Weight: 254.322 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	432.1±45.0 °C at 760 mmHg
Density	1.1±0.1 g/cm3
Flash Point	159.2±22.2 °C
Exact Mass	254.151810
PSA	63.60000
LogP	3.65
Vapor Pressure	0.0±2.2 mmHg at 25°C
Refractive Index	1.489

Activity & Biological Data

Target	IC50: 35 μM (PC3 cell)[1]
Additional Information	[1]. Rae C, et al. Inhibition of Fatty Acid Synthase Sensitizes Prostate Cancer Cells to Radiotherapy. [2]. Makowski K, et al. Differential pharmacologic properties of the two C75 enantiomers: (+)-C75 is a strong anorectic drug; (-)-C75 has antitumor activity. Chirality. 2013 May;25(5):281-7. [3]. Gao S, et al. Effect of the anorectic fatty acid synthase inhibitor C75 on neuronal activity in the hypothalamus and brainstem. Proc Natl Acad Sci U S A. 2003 May 13;100(10):5628-33. [4]. Thupari JN, et al. C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9498-502.

Target

IC50: 35 μM (PC3 cell)[1]

Additional Information

[1]. Rae C, et al. Inhibition of Fatty Acid Synthase Sensitizes Prostate Cancer Cells to Radiotherapy. [2]. Makowski K, et al. Differential pharmacologic properties of the two C75 enantiomers: (+)-C75 is a strong anorectic drug; (-)-C75 has antitumor activity. Chirality. 2013 May;25(5):281-7. [3]. Gao S, et al. Effect of the anorectic fatty acid synthase inhibitor C75 on neuronal activity in the hypothalamus and brainstem. Proc Natl Acad Sci U S A. 2003 May 13;100(10):5628-33. [4]. Thupari JN, et al. C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity. Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9498-502.

Customs & Trade Information

HS Code	2932190090
Summary	2932190090 other compounds containing an unfused furan ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Frequently Asked Questions

What is the CAS number of trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic acid?

The CAS number of trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic acid is 191282-48-1.

What are the molecular formula and molecular weight of trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic acid?

trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic acid has molecular formula C14H22O4 and molecular weight 254.322 g/mol.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "trans-Tetrahydro-4-methylene-2-octyl-5-oxo-3-furancarboxylic acid (CAS 191282-48-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-49772-9 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.