Eltoprazine

Also known as: 1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine, DU 28853, 1-(1,4-benzodioxan-5-yl)piperazine, Eltoprazine [INN], Eltoprazina, Eltoprazinum

Eltoprazine (CAS 98224-03-4) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C12H16N2O2 and a molecular weight of 220.26800 g/mol. Key properties include a boiling point of 384.3ºC at 760mmHg, a density of 1.18g/cm3 and a flash point of 186.2ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 98224-03-4
Jingsj CID: J-49723-4
Molecular Formula: C₁₂H₁₆N₂O₂
Molecular Weight: 220.26800 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	384.3ºC at 760mmHg
Density	1.18g/cm3
Flash Point	186.2ºC
Exact Mass	220.12100
PSA	33.73000
LogP	1.26120

Activity & Biological Data

Additional Information	[1]. Sijbesma H, et al. Eltoprazine, a drug which reduces aggressive behaviour, binds selectively to 5-HT1 receptor sites in the rat brain: an autoradiographic study. Eur J Pharmacol. 1990 Feb 20;177(1-2):55-66. [2]. Joels M, et al. Eltoprazine suppresses hyperpolarizing responses to serotonin in rat hippocampus. J Pharmacol Exp Ther. 1990 Apr;253(1):284-9. [3]. Bezard E, et al. Study of the antidyskinetic effect of eltoprazine in animal models of levodopa-induced dyskinesia. Mov Disord. 2013 Jul;28(8):1088-96. [4]. Rocha B, et al. Chronic mianserin or eltoprazine treatment in rats: effects on the elevated plus-maze test and on limbic 5-HT2C receptor levels. Eur J Pharmacol. 1994 Sep 1;262(1-2):125-31.

Additional Information

[1]. Sijbesma H, et al. Eltoprazine, a drug which reduces aggressive behaviour, binds selectively to 5-HT1 receptor sites in the rat brain: an autoradiographic study. Eur J Pharmacol. 1990 Feb 20;177(1-2):55-66. [2]. Joels M, et al. Eltoprazine suppresses hyperpolarizing responses to serotonin in rat hippocampus. J Pharmacol Exp Ther. 1990 Apr;253(1):284-9. [3]. Bezard E, et al. Study of the antidyskinetic effect of eltoprazine in animal models of levodopa-induced dyskinesia. Mov Disord. 2013 Jul;28(8):1088-96. [4]. Rocha B, et al. Chronic mianserin or eltoprazine treatment in rats: effects on the elevated plus-maze test and on limbic 5-HT2C receptor levels. Eur J Pharmacol. 1994 Sep 1;262(1-2):125-31.

Customs & Trade Information

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Eltoprazine?

The CAS number of Eltoprazine is 98224-03-4.

What are the molecular formula and molecular weight of Eltoprazine?

Eltoprazine has molecular formula C12H16N2O2 and molecular weight 220.26800 g/mol.

What are the upstream and downstream products of Eltoprazine?

For Eltoprazine, Upstream Products: Bis(2-chloroethyl)amine hydrochloride, 5-Amino-1,4-benzodioxane, 5-Bromo-2,3-dihydro-1,4-benzodioxine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Eltoprazine (CAS 98224-03-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-49723-4 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.