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4-Chloro-6-fluoroquinoline

Also known as: Quinoline, 4-chloro-6-fluoro-, 4-Chloro-6-fluoroquinoline, MFCD00278783, EOS-62017, BUTTPARK 20\09-07

4-Chloro-6-fluoroquinoline (CAS 391-77-5) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C9H5ClFN and a molecular weight of 181.594 g/mol. Key properties include a melting point of 95 °C, a boiling point of 259.9±20.0 °C at 760 mmHg, a density of 1.4±0.1 g/cm3 and a flash point of 111.0±21.8 °C. It is classified under GHS with signal word Danger and hazard statements H302 — Harmful if swallowed, H315 — Causes skin irritation and H318 — Causes serious eye damage. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
391-77-5
Jingsj CID
J-49417-7
Molecular Formula
C9H5ClFN
Molecular Weight
181.594 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Melting Point95 °C
Boiling Point259.9±20.0 °C at 760 mmHg
Density1.4±0.1 g/cm3
Flash Point111.0±21.8 °C
Exact Mass181.009460
PSA12.89000
LogP2.86
Vapor Pressure0.0±0.5 mmHg at 25°C
Refractive Index1.626
Storage Conditions2-8°C

GHS Safety & Compliance

Corrosion / IrritantSignal word: Danger
  • H302 — Harmful if swallowed
  • H315 — Causes skin irritation
  • H318 — Causes serious eye damage
  • H335 — May cause respiratory irritation

Frequently Asked Questions

What is the CAS number of 4-Chloro-6-fluoroquinoline?

The CAS number of 4-Chloro-6-fluoroquinoline is 391-77-5.

What are the molecular formula and molecular weight of 4-Chloro-6-fluoroquinoline?

4-Chloro-6-fluoroquinoline has molecular formula C9H5ClFN and molecular weight 181.594 g/mol.

Is 4-Chloro-6-fluoroquinoline hazardous?

4-Chloro-6-fluoroquinoline has GHS signal word Danger and hazard statements H302 — Harmful if swallowed; H315 — Causes skin irritation; H318 — Causes serious eye damage.

What are the upstream and downstream products of 4-Chloro-6-fluoroquinoline?

For 4-Chloro-6-fluoroquinoline, Upstream Products: 6-fluoro-4-hydroxyquinoline, 6-Fluoro-4-hydroxyquinoline-3-carboxylic acid, Ethyl 6-fluoro-4-hydroxy-3-quinolinecarboxylate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "4-Chloro-6-fluoroquinoline (CAS 391-77-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-49417-7 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.