Vesnarinone

Also known as: OPC-8212, Piteranometozine, Arkin, Arkin-Z, DRG-0210, 6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-3,4-dihydro-2(1H)-quinolinone, 3,4-Dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)-quinolinone

Vesnarinone (CAS 81840-15-5) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C22H25N3O4 and a molecular weight of 395.45200 g/mol. Key properties include a melting point of 238.1-239.5° (Tominaga); mp 238.1-239.8° (Shimizu), a boiling point of 678.3ºC at 760 mmHg, a density of 1.246g/cm3 and a flash point of 364ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 81840-15-5
Jingsj CID: J-49199-6
Molecular Formula: C₂₂H₂₅N₃O₄
Molecular Weight: 395.45200 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	238.1-239.5° (Tominaga); mp 238.1-239.8° (Shimizu)
Boiling Point	678.3ºC at 760 mmHg
Density	1.246g/cm3
Flash Point	364ºC
Exact Mass	395.18500
PSA	71.11000
LogP	2.69180
Refractive Index	1.601
Storage Conditions	2-8℃

Activity & Biological Data

Additional Information	[1]. Katayama Y, et al. Inhibitory effects of Vesnarinone on cloned cardiac delayed rectifier K(+) channels expressed in a mammalian cell line. J Pharmacol Exp Ther. 2000 Jul;294(1):339-46. [2]. Inage M, et al. Vesnarinone represses the fibrotic changes in murine lung injury induced by bleomycin. Int J Biol Sci. 2009;5(4):304-10. [3]. Cavusoglu E, et al. Vesnarinone: a new inotropic agent for treating congestive heart failure. J Card Fail. 1995 Jun;1(3):249-57. [4]. Matsumori A, et al. Vesnarinone, a new inotropic agent, inhibits cytokine production by stimulated human blood from patients with heart failure. Circulation. 1994 Mar;89(3):955-8.

Additional Information

[1]. Katayama Y, et al. Inhibitory effects of Vesnarinone on cloned cardiac delayed rectifier K(+) channels expressed in a mammalian cell line. J Pharmacol Exp Ther. 2000 Jul;294(1):339-46. [2]. Inage M, et al. Vesnarinone represses the fibrotic changes in murine lung injury induced by bleomycin. Int J Biol Sci. 2009;5(4):304-10. [3]. Cavusoglu E, et al. Vesnarinone: a new inotropic agent for treating congestive heart failure. J Card Fail. 1995 Jun;1(3):249-57. [4]. Matsumori A, et al. Vesnarinone, a new inotropic agent, inhibits cytokine production by stimulated human blood from patients with heart failure. Circulation. 1994 Mar;89(3):955-8.

Frequently Asked Questions

What is the CAS number of Vesnarinone?

The CAS number of Vesnarinone is 81840-15-5.

What are the molecular formula and molecular weight of Vesnarinone?

Vesnarinone has molecular formula C22H25N3O4 and molecular weight 395.45200 g/mol.

What are the upstream and downstream products of Vesnarinone?

For Vesnarinone, Upstream Products: 6-Amino-3,4-dihydroquinolin-2(1H)-one, 3,4-Dimethoxybenzoyl chloride, Bis(2-bromoethyl)amine hydrobromide; Downstream Products: Ethyl 3,4-dimethoxybenzoate, Veratric acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Vesnarinone (CAS 81840-15-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-49199-6 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.