Enprofylline

Also known as: 3-propylxanthine, 3,7-dihydro-3-propyl-1H-purine-2,6-dione, 3-n-propylxanthine, 3-propyl-7H-purine-2,6-dione, D 4028, Nilyph, Oxeze, enprophylline, 3-propyl-1H-purine-2,6(3H,9H)-dione, 1H-purine-2,6-dione, 3,7-dihydro-3-propyl-, 3-propyl-2,3,6,9-tetrahydro-1H-purine-2,6-dione, 3,9-dihydro-3-propyl-1H-purine-2,6-dione, 3-propyl-7H-purine-2,6-quinone, enprofyllilie, 3-propyl-1H-purine-2,6(3H,7H)-dione, 3-propylxanthfine, 1H-purine-2,6-dione, 3,9-dihydro-3-propyl-, EINECS 255-201-8, MFCD00043205, Enprofilina

Enprofylline (CAS 41078-02-8) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C8H10N4O2 and a molecular weight of 194.19100 g/mol. Key property: a density of 1.367 g/cm3. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 41078-02-8
Jingsj CID: J-49121-4
Molecular Formula: C₈H₁₀N₄O₂
Molecular Weight: 194.19100 g/mol
Category: Organic Bases
Last updated: 8/21/2026

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Physicochemical Properties

Density	1.367 g/cm3
Exact Mass	194.08000
PSA	83.54000
Refractive Index	1.583

Activity & Biological Data

Target	A2B receptor:7 μM (Ki)
Additional Information	[1]. I Feoktistov, et al. Adenosine A2b receptors evoke interleukin-8 secretion in human mast cells. An enprofylline-sensitive mechanism with implications for asthma. J Clin Invest. 1995 Oct;96(4):1979-86. [2]. M B Grant, et al. Proliferation, migration, and ERK activation in human retinal endothelial cells through A(2B) adenosine receptor stimulation. Invest Ophthalmol Vis Sci. 2001 Aug;42(9):2068-73. [3]. Jiang-Ning Yang, et al. Physiological roles of A1 and A2A adenosine receptors in regulating heart rate, body temperature, and locomotion as revealed using knockout mice and caffeine. Am J Physiol Heart Circ Physiol. 2009 Apr;296(4):H1141-9.

Target

A2B receptor:7 μM (Ki)

Additional Information

[1]. I Feoktistov, et al. Adenosine A2b receptors evoke interleukin-8 secretion in human mast cells. An enprofylline-sensitive mechanism with implications for asthma. J Clin Invest. 1995 Oct;96(4):1979-86. [2]. M B Grant, et al. Proliferation, migration, and ERK activation in human retinal endothelial cells through A(2B) adenosine receptor stimulation. Invest Ophthalmol Vis Sci. 2001 Aug;42(9):2068-73. [3]. Jiang-Ning Yang, et al. Physiological roles of A1 and A2A adenosine receptors in regulating heart rate, body temperature, and locomotion as revealed using knockout mice and caffeine. Am J Physiol Heart Circ Physiol. 2009 Apr;296(4):H1141-9.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Enprofylline?

The CAS number of Enprofylline is 41078-02-8.

What are the molecular formula and molecular weight of Enprofylline?

Enprofylline has molecular formula C8H10N4O2 and molecular weight 194.19100 g/mol.

What are the upstream and downstream products of Enprofylline?

For Enprofylline, Upstream Products: Diethoxymethyl acetate, 6-Amino-1-propylpyrimidine-2,4(1H,3H)-dione; Downstream Products: 1,3-Dipropyl-7-methylxanthine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Enprofylline (CAS 41078-02-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-49121-4 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.