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D-Penicillamine

Also known as: 3,3-Dimethyl-D-cysteine, 3-Mercapto-D-valine, D-(-)-2-Amino-3-mercapto-3-methylbutanoic acid, D-β,β-Dimethylcysteine, β-Mercaptovaline, H-D-Pen-OH, Cuprimine, Depen, Cuprenil, Metalcaptase, Trolovol, (2R)-2-amino-3-mercapto-3-methylbutanoic acid

D-Penicillamine (CAS 52-67-5) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C5H11NO2S and a molecular weight of 149.211 g/mol. Key properties include a melting point of 210 °C (dec.)(lit.), a boiling point of 251.8±35.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 106.1±25.9 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
52-67-5
Jingsj CID
J-48812-0
Molecular Formula
C5H11NO2S
Molecular Weight
149.211 g/mol
Category
Organic Bases
Last updated
8/21/2026

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Physicochemical Properties

Melting Point210 °C (dec.)(lit.)
Boiling Point251.8±35.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point106.1±25.9 °C
Exact Mass149.051056
PSA102.12000
LogP0.93
Vapor Pressure0.0±1.1 mmHg at 25°C
Refractive Index1.528
Additional Property11.1 g/100 mL (20 ºC)

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

Additional Information[1]. Peisach, J. and W.E. Blumberg, A mechanism for the action of penicillamine in the treatment of Wilson's disease. Mol Pharmacol, 1969. 5(2): p. 200-9. [2]. Jaffe, I.A., K. Altman, and P. Merryman, The Antipyridoxine Effect of Penicillamine in Man. J Clin Invest, 1964. 43: p. 1869-73. [3]. Camp, A.V., Penicillamine in the treatment of rheumatoid arthritis. Proc R Soc Med, 1977. 70(2): p. 67-9.

Customs & Trade Information

HS Code2930909090
Summary2930909090. other organo-sulphur compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of D-Penicillamine?

The CAS number of D-Penicillamine is 52-67-5.

What are the molecular formula and molecular weight of D-Penicillamine?

D-Penicillamine has molecular formula C5H11NO2S and molecular weight 149.211 g/mol.

Is D-Penicillamine hazardous?

D-Penicillamine has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of D-Penicillamine?

For D-Penicillamine, Upstream Products: 2-Aminothiophenol, o-Toluidine, p-Toluidine; Downstream Products: 2-Benzyl-1,3-thiazole-4-carboxylic acid, D-Valine, L-Valine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "D-Penicillamine (CAS 52-67-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-48812-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.