2-Benzoxazolinone

Also known as: 2(3H)-Benzoxazolone, 2-Hydroxybenzoxazole, 1,3-Benzoxazol-2(3H)-one, 2,3-Dihydro-2-oxo-1,3-benzoxazole, Benzoxazolinone, Benzoxazol-2(3H)-one, Benzoxazole-2-ol, 3H-1,3-Benzoxazol-2-one, 2-Benzoxazolone, 2-Benzoxazolol, USAF ek-5429

2-Benzoxazolinone (CAS 59-49-4) is a compound in the Ketones category listed in the Jingsj chemical database. It has the molecular formula C7H5NO2 and a molecular weight of 135.120 g/mol. Key properties include a melting point of 137-139 °C(lit.), a boiling point of 299ºC at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 160 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 59-49-4
Jingsj CID: J-48744-5
Molecular Formula: C₇H₅NO₂
Molecular Weight: 135.120 g/mol
Category: Ketones
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	137-139 °C(lit.)
Boiling Point	299ºC at 760 mmHg
Density	1.3±0.1 g/cm3
Flash Point	160 °C
Exact Mass	135.032028
PSA	46.00000
LogP	1.16
Refractive Index	1.586
Additional Property	soluble in hot water

Activity & Biological Data

Target	LC50: 40 μg/mL (L. donovani)[1]
Additional Information	[1]. Kapil A, et al. Leishmanicidal activity of 2-benzoxazolinone from Acanthus illicifolius in vitro. Planta Med. 1994 Apr;60(2):187-8. [2]. Batish DR, et al. 2-Benzoxazolinone (BOA) induced oxidative stress, lipid peroxidation and changes in some antioxidant enzyme activities in mung bean (Phaseolus aureus). Plant Physiology and Biochemistry 44(11-12):819-27 [3]. Krawiecka M, et al. Synthesis and biological activity of novel series of 1,3-benzoxazol-2(3H)-one derivatives. Acta Pol Pharm. 2013 Mar-Apr;70(2):245-53. [4]. Miandji AM, et al. Synthesis and biological activities of some 1,3-benzoxazol-2(3H)-one derivatives as anti-quorum sensing agents. Arzneimittelforschung. 2012 Jul;62(7):330-4.

Target

LC50: 40 μg/mL (L. donovani)[1]

Additional Information

[1]. Kapil A, et al. Leishmanicidal activity of 2-benzoxazolinone from Acanthus illicifolius in vitro. Planta Med. 1994 Apr;60(2):187-8. [2]. Batish DR, et al. 2-Benzoxazolinone (BOA) induced oxidative stress, lipid peroxidation and changes in some antioxidant enzyme activities in mung bean (Phaseolus aureus). Plant Physiology and Biochemistry 44(11-12):819-27 [3]. Krawiecka M, et al. Synthesis and biological activity of novel series of 1,3-benzoxazol-2(3H)-one derivatives. Acta Pol Pharm. 2013 Mar-Apr;70(2):245-53. [4]. Miandji AM, et al. Synthesis and biological activities of some 1,3-benzoxazol-2(3H)-one derivatives as anti-quorum sensing agents. Arzneimittelforschung. 2012 Jul;62(7):330-4.

Customs & Trade Information

HS Code	2934999090
Summary	2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 2-Benzoxazolinone?

The CAS number of 2-Benzoxazolinone is 59-49-4.

What are the molecular formula and molecular weight of 2-Benzoxazolinone?

2-Benzoxazolinone has molecular formula C7H5NO2 and molecular weight 135.120 g/mol.

What are the upstream and downstream products of 2-Benzoxazolinone?

For 2-Benzoxazolinone, Upstream Products: Bis(trichloromethyl) carbonate, 2-Aminophenol, 2-Nitrophenol; Downstream Products: 3-Propionyl-2-benzoxazolinone, 6-Nitro-1,3-benzoxazol-2(3H)-one, (6-Nitro-2-oxo-1,3-benzoxazol-3(2H)-yl)acetic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "2-Benzoxazolinone (CAS 59-49-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-48744-5 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.