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Oxindole

Also known as: 2-Oxindole, Indolin-2-one, 1,3-Dihydro-2H-indol-2-one, 2-Indolinone, 2-Oxoindoline, 2-Hydroxyindole, 2-Ketoindoline, 2-Indolone, 2-Oxiindole, 3H-Indol-2-ol

Oxindole (CAS 59-48-3) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C8H7NO and a molecular weight of 133.147 g/mol. Key properties include a melting point of 123-128 °C(lit.), a boiling point of 312.8±45.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 190.0±18.0 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
59-48-3
Jingsj CID
J-48742-5
Molecular Formula
C8H7NO
Molecular Weight
133.147 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Melting Point123-128 °C(lit.)
Boiling Point312.8±45.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point190.0±18.0 °C
Exact Mass133.052765
PSA29.10000
LogP0.61
Vapor Pressure0.0±0.7 mmHg at 25°C
Refractive Index1.640
Additional Propertyinsoluble

GHS Safety & Compliance

IrritantSignal word: Warning
  • H302 — Harmful if swallowed

Activity & Biological Data

Additional Information[1]. Leoni A, et al. 2-Indolinone a versatile scaffold for treatment of cancer: a patent review (2008-2014). Expert Opin Ther Pat. 2016;26(2):149-73. [2]. Kaur M, et al. Oxindole: A chemical prism carrying plethora of therapeutic benefits. Eur J Med Chem. 2016 Nov 10;123:858-894.

Customs & Trade Information

HS Code2933790090
Summary2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Oxindole?

The CAS number of Oxindole is 59-48-3.

What are the molecular formula and molecular weight of Oxindole?

Oxindole has molecular formula C8H7NO and molecular weight 133.147 g/mol.

Is Oxindole hazardous?

Oxindole has GHS signal word Warning and hazard statements H302 — Harmful if swallowed.

What are the upstream and downstream products of Oxindole?

For Oxindole, Upstream Products: isatin, Indole, methyl 2-(2-nitrophenyl)acetate; Downstream Products: 1,3-Dihydro-2H-indole-2-thione, Indoline, 2-Aminophenylacetic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Oxindole (CAS 59-48-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-48742-5 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.