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Methyl hydrogen phthalate

Also known as: mono-Methyl phthalate, Monomethyl phthalate, 1,2-Benzenedicarboxylic acid, monomethyl ester, 2-(Methoxycarbonyl)benzoic acid, 2-methoxycarbonylbenzoic acid, Methyl 2-Carboxybenzoate, Phthalic acid monomethyl ester, Phthalic acid methyl ester, NSC 8281, MFCD00002466

Methyl hydrogen phthalate (CAS 4376-18-5) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C9H8O4 and a molecular weight of 180.157 g/mol. Key properties include a melting point of 82-84 °C(lit.), a boiling point of 328.9±25.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 134.7±16.7 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
4376-18-5
Jingsj CID
J-48437-7
Molecular Formula
C9H8O4
Molecular Weight
180.157 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point82-84 °C(lit.)
Boiling Point328.9±25.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point134.7±16.7 °C
Exact Mass180.042252
PSA63.60000
LogP1.13
Vapor Pressure0.0±0.8 mmHg at 25°C
Refractive Index1.556

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

Additional Information[1]. Chong Liu, et al. Urinary biomarkers of phthalates exposure and risks of thyroid cancer and benign nodule. J Hazard Mater. 2020 Feb 5;383:121189.

Frequently Asked Questions

What is the CAS number of Methyl hydrogen phthalate?

The CAS number of Methyl hydrogen phthalate is 4376-18-5.

What are the molecular formula and molecular weight of Methyl hydrogen phthalate?

Methyl hydrogen phthalate has molecular formula C9H8O4 and molecular weight 180.157 g/mol.

Is Methyl hydrogen phthalate hazardous?

Methyl hydrogen phthalate has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

What are the upstream and downstream products of Methyl hydrogen phthalate?

For Methyl hydrogen phthalate, Upstream Products: Dimethyl phthalate, Carbon dioxide, Methyl 2-iodobenzoate; Downstream Products: (-)-Mono-(1R)-menthyl phthalate, Phthalic anhydride, Methyl trifluoroacetate.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Methyl hydrogen phthalate (CAS 4376-18-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-48437-7 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.