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2-(Trifluoromethyl)pyridine

Also known as: alpha,alpha,alpha-Trifluoro-2-picoline, 2-(CF3)-Pyridine, 6-trifluoromethylpyridine, o-Trifluormethylpyridine, 2-trifluoromethylpyridine

2-(Trifluoromethyl)pyridine (CAS 368-48-9) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C6H4F3N and a molecular weight of 147.098 g/mol. Key properties include a boiling point of 115.3±35.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 23.5±25.9 °C. It is classified under GHS with signal word Warning and hazard statements H226 — Flammable liquid and vapour, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
368-48-9
Jingsj CID
J-48219-9
Molecular Formula
C6H4F3N
Molecular Weight
147.098 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point115.3±35.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point23.5±25.9 °C
Exact Mass147.029587
PSA12.89000
LogP1.70
Vapor Pressure22.8±0.2 mmHg at 25°C
Refractive Index1.419

GHS Safety & Compliance

Flammable / IrritantSignal word: Warning
  • H226 — Flammable liquid and vapour
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Customs & Trade Information

HS Code2933399090
Summary2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 2-(Trifluoromethyl)pyridine?

The CAS number of 2-(Trifluoromethyl)pyridine is 368-48-9.

What are the molecular formula and molecular weight of 2-(Trifluoromethyl)pyridine?

2-(Trifluoromethyl)pyridine has molecular formula C6H4F3N and molecular weight 147.098 g/mol.

Is 2-(Trifluoromethyl)pyridine hazardous?

2-(Trifluoromethyl)pyridine has GHS signal word Warning and hazard statements H226 — Flammable liquid and vapour; H315 — Causes skin irritation; H319 — Causes serious eye irritation.

What are the upstream and downstream products of 2-(Trifluoromethyl)pyridine?

For 2-(Trifluoromethyl)pyridine, Upstream Products: 2-Bromopyridine, Trimethyl(trifluoromethyl)silane, Methyl trifluoroacetate; Downstream Products: 2-(Trifluoromethyl)pyridin-3-ol, 2-(Trifluoromethyl)pyridine 1-oxide, 4-Iodo-2-(trifluoromethyl)pyridine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "2-(Trifluoromethyl)pyridine (CAS 368-48-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-48219-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.