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3-Chloro-4-fluoroaniline

Also known as: 3-Chloro-4-fluorobenzenamine, 3-Chloro-4-fluorophenylamine, 3-Chlor-4-fluoranilin, 3-Cl-4-F-aniline, 4-Fluoro-3-chloroaniline, Benzenamine, 3-chloro-4-fluoro-, CHLOROFLUOROANILINE, Fluorochloroaniline, EINECS 206-682-8, MFCD00007767

3-Chloro-4-fluoroaniline (CAS 367-21-5) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C6H5ClFN and a molecular weight of 145.56 g/mol. Key properties include a melting point of 42-44 °C(lit.), a boiling point of 227.5±0.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 99.4±21.8 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed, H311 — Toxic in contact with skin and H331 — Toxic if inhaled. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
367-21-5
Jingsj CID
J-48204-2
Molecular Formula
C6H5ClFN
Molecular Weight
145.56 g/mol
Category
Organic Bases
Last updated
8/21/2026

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Physicochemical Properties

Melting Point42-44 °C(lit.)
Boiling Point227.5±0.0 °C at 760 mmHg
Density1.3±0.1 g/cm3
Flash Point99.4±21.8 °C
Exact Mass145.009460
PSA26.02000
LogP2.14
Vapor Pressure0.1±0.4 mmHg at 25°C
Refractive Index1.570
StabilityStable. Incompatible with strong oxidizing agents, acids, acid chlorides, acid anhydrides, chloroformates. May be air-sensitive.
Additional Property10 g/L (20 ºC)

GHS Safety & Compliance

Acute Toxicity / Health HazardSignal word: Danger
  • H301 — Toxic if swallowed
  • H311 — Toxic in contact with skin
  • H331 — Toxic if inhaled
  • H373 — May cause damage to organs through prolonged exposure

Customs & Trade Information

HS Code2921420090
SummaryHS:2921420090 aniline derivatives and their salts VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 3-Chloro-4-fluoroaniline?

The CAS number of 3-Chloro-4-fluoroaniline is 367-21-5.

What are the molecular formula and molecular weight of 3-Chloro-4-fluoroaniline?

3-Chloro-4-fluoroaniline has molecular formula C6H5ClFN and molecular weight 145.56 g/mol.

Is 3-Chloro-4-fluoroaniline hazardous?

3-Chloro-4-fluoroaniline has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H311 — Toxic in contact with skin; H331 — Toxic if inhaled.

What are the upstream and downstream products of 3-Chloro-4-fluoroaniline?

For 3-Chloro-4-fluoroaniline, Upstream Products: 2-Chloro-1-fluoro-4-nitrobenzene, 1-Fluoro-4-nitrobenzene, 1-Chloro-3-nitrobenzene; Downstream Products: 1-Chloro-2-fluorobenzene, 6-amino-4-(3-chloro-4-fluorophenylamino)-7-ethoxyquinoline-3-carbonitrile, 4-Bromo-2-chloro-1-fluorobenzene.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "3-Chloro-4-fluoroaniline (CAS 367-21-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-48204-2 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.