Cyclen
Also known as: 1,4,7,10-Tetraazacyclododecane, 1,4,7,10-Tetrazacyclododecane, Tetraaza-12-crown-4, [12]aneN4, Cyclen(M-100), Kryptofix 11 aza
Cyclen (CAS 294-90-6) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C8H20N4 and a molecular weight of 172.27 g/mol. Key properties include a melting point of 110-113 °C(lit.), a boiling point of 283.8±8.0 °C at 760 mmHg, a density of 0.9±0.1 g/cm3 and a flash point of 129.5±13.5 °C. It is classified under GHS with signal word Danger and hazard statements H302 — Harmful if swallowed, H312 — Harmful in contact with skin and H314 — Causes severe skin burns and eye damage. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 294-90-6
- Jingsj CID
- J-47852-4
- Molecular Formula
- C8H20N4
- Molecular Weight
- 172.27 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 110-113 °C(lit.) |
|---|---|
| Boiling Point | 283.8±8.0 °C at 760 mmHg |
| Density | 0.9±0.1 g/cm3 |
| Flash Point | 129.5±13.5 °C |
| Exact Mass | 172.168793 |
| PSA | 48.12000 |
| LogP | -2.34 |
| Vapor Pressure | 0.0±0.6 mmHg at 25°C |
| Refractive Index | 1.424 |
| Storage Conditions | Refrigerator |
GHS Safety & Compliance
- H302 — Harmful if swallowed
- H312 — Harmful in contact with skin
- H314 — Causes severe skin burns and eye damage
- H410 — Very toxic to aquatic life with long lasting effects
Activity & Biological Data
| Additional Information | [1]. Rashid HU, et al. Cyclen-based Gd3+ complexes as MRI contrast agents: Relaxivity enhancement and ligand design. Bioorg Med Chem. 2016 Nov 15;24(22):5663-5684. |
|---|
Customs & Trade Information
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Cyclen?
The CAS number of Cyclen is 294-90-6.
What are the molecular formula and molecular weight of Cyclen?
Cyclen has molecular formula C8H20N4 and molecular weight 172.27 g/mol.
Is Cyclen hazardous?
Cyclen has GHS signal word Danger and hazard statements H302 — Harmful if swallowed; H312 — Harmful in contact with skin; H314 — Causes severe skin burns and eye damage.
What are the upstream and downstream products of Cyclen?
For Cyclen, Upstream Products: 1,4,7,10-Tetrakis(4-methylbenzenesulfonyl)-1,4,7,10-tetraazacyclododecane, Triethylenetetramine, 1,4,7,10-Tetraazacyclododecane tetrahydrochloride; Downstream Products: 1,4,7,10-tetrabenzyl-1,4,7,10-tetraazacyclododecane, DOTA, prop-2-enyl 2-(1,4,7,10-tetraazacyclododecan-1-yl)acetate.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Cyclen (CAS 294-90-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-47852-4 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.