Timolol maleate
Also known as: (S)-Timolol maleate, (-)-Timolol Maleate, (2S)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol (2Z)-but-2-enedioate (1:1), Timolol hydrogenmaleate, Timolol maleate salt, Betim, Optimol, Temserin, Tenopt, Timacar, Timorom, Aquanil, Proflax, Rysmon TG
Timolol maleate (CAS 26921-17-5) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C17H28N4O7S and a molecular weight of 432.492 g/mol. Key properties include a melting point of 202-203 °C(lit.), a boiling point of 704.6ºC at 760 mmHg and a flash point of 380ºC. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed and H361 — Suspected of damaging fertility or the unborn child. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 26921-17-5
- Jingsj CID
- J-47553-6
- Molecular Formula
- C17H28N4O7S
- Molecular Weight
- 432.492 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 202-203 °C(lit.) |
|---|---|
| Boiling Point | 704.6ºC at 760 mmHg |
| Flash Point | 380ºC |
| Exact Mass | 432.167877 |
| PSA | 182.58000 |
| LogP | 0.67020 |
| Appearance | powder | white to off-white |
| Vapor Pressure | 7.7E-21mmHg at 25°C |
| Additional Property | H2O: soluble |
GHS Safety & Compliance
- H302 — Harmful if swallowed
- H361 — Suspected of damaging fertility or the unborn child
Activity & Biological Data
| Additional Information | [1]. Deepika Aggarwal, Indu P. Kaur. Improved pharmacodynamics of timolol maleate from a mucoadhesive niosomal ophthalmic drug delivery system. International Journal of Pharmaceutics. 2005, 290(1-2): 155-159. [2]. Mandagere AK, Thompson TN, Hwang KK. Graphical model for estimating oral bioavailability of drugs in humans and other species from their Caco-2 permeability and in vitro liver enzyme metabolic stability rates. J Med Chem. 2002;45(2):304-11. [3]. A.H El-Kamel. In vitro and in vivo evaluation of Pluronic F127-based ocular delivery system for timolol maleate. International Journal of Pharmaceutics. 2002, 241, (1) :47-55. [4]. Konstas AG, Maltezos AC, Gandi S, et al. Comparison of 24-hour intraocular pressure reduction with two dosing regimens of latanoprost and timolol maleate in patients with primary open-angle glaucoma. American Journal of Ophthalmology .1999, 128(1):15-20. |
|---|
Customs & Trade Information
| HS Code | 2934999090 |
|---|---|
| Summary | 2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of Timolol maleate?
The CAS number of Timolol maleate is 26921-17-5.
What are the molecular formula and molecular weight of Timolol maleate?
Timolol maleate has molecular formula C17H28N4O7S and molecular weight 432.492 g/mol.
Is Timolol maleate hazardous?
Timolol maleate has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H361 — Suspected of damaging fertility or the unborn child.
What are the upstream and downstream products of Timolol maleate?
For Timolol maleate, Upstream Products: 4-(Morpholin-4-yl)-1,2,5-thiadiazol-3-ol, 3-Chloro-4-morpholino-1,2,5-thiadiazole, Timolol.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Timolol maleate (CAS 26921-17-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-47553-6 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.