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Loxoprofen

Also known as: 2-[4-(2-Oxocyclopentan-1-ylmethyl)phenyl]propionic acid, 2-{4-[(2-Oxocyclopentyl)methyl]phenyl}propanoic acid, α-Methyl-4-[(2-oxocyclopentyl)methyl]benzeneacetic acid, Loxoprofen Acid, IOXOPROFEN, KOLOXO, loxoprofen

Loxoprofen (CAS 68767-14-6) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C15H18O3 and a molecular weight of 246.302 g/mol. Key properties include a melting point of 108.5 - 111ºC, a boiling point of 417.9±20.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 220.7±18.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
68767-14-6
Jingsj CID
J-47524-2
Molecular Formula
C15H18O3
Molecular Weight
246.302 g/mol
Category
Organic Compounds
Last updated
8/21/2026

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Physicochemical Properties

Melting Point108.5 - 111ºC
Boiling Point417.9±20.0 °C at 760 mmHg
Density1.2±0.1 g/cm3
Flash Point220.7±18.3 °C
Exact Mass246.125595
PSA54.37000
LogP1.87
Vapor Pressure0.0±1.0 mmHg at 25°C
Refractive Index1.568

Activity & Biological Data

TargetCOX-1:6.5 μM (IC50, in human whole blood) COX-2:13.5 μM (IC50, in human whole blood)
Additional Information[1]. Riendeau D, et al. Evaluation of loxoprofen and its alcohol metabolites for potency and selectivity of inhibition of cyclooxygenase-2. Bioorg Med Chem Lett. 2004 Mar 8;14(5):1201-3.

Customs & Trade Information

HS Code2918300090
Summary2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Loxoprofen?

The CAS number of Loxoprofen is 68767-14-6.

What are the molecular formula and molecular weight of Loxoprofen?

Loxoprofen has molecular formula C15H18O3 and molecular weight 246.302 g/mol.

What are the upstream and downstream products of Loxoprofen?

For Loxoprofen, Upstream Products: 2-Benzylcyclopentanone, Benzeneacetic acid, 4-(chloromethyl)-α-methyl-, ethyl ester, Ethyl 2-oxocyclopentanecarboxylate; Downstream Products: Loxoprofen sodium.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Loxoprofen (CAS 68767-14-6)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-47524-2 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.