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Methylmalonic acid

Also known as: 2-Methylpropanedioic acid, Isosuccinic acid, 2-Methylmalonic acid, 1,1-Ethanedicarboxylic acid, Malonic acid, methyl-, Methylpropanedioic acid, Propanedioic acid, 2-methyl-

Methylmalonic acid (CAS 516-05-2) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C4H6O4 and a molecular weight of 118.088 g/mol. Key properties include a melting point of 129-136 ºC, a boiling point of 334.4±25.0 °C at 760 mmHg, a density of 1.45 and a flash point of 170.2±19.7 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
516-05-2
Jingsj CID
J-47395-0
Molecular Formula
C4H6O4
Molecular Weight
118.088 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point129-136 ºC
Boiling Point334.4±25.0 °C at 760 mmHg
Density1.45
Flash Point170.2±19.7 °C
Exact Mass118.026611
PSA74.60000
LogP-0.21
Vapor Pressure0.0±1.5 mmHg at 25°C
Refractive Index1.474
Additional Propertysoluble

GHS Safety & Compliance

IrritantSignal word: Warning
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Activity & Biological Data

TargetHuman Endogenous Metabolite
Additional Information[1]. Vashi P, et al. Methylmalonic Acid and Homocysteine as Indicators of Vitamin B-12 Deficiency in Cancer. PLoS One. 2016 Jan 25;11(1):e0147843.

Customs & Trade Information

HS Code2917190090
Summary2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of Methylmalonic acid?

The CAS number of Methylmalonic acid is 516-05-2.

What are the molecular formula and molecular weight of Methylmalonic acid?

Methylmalonic acid has molecular formula C4H6O4 and molecular weight 118.088 g/mol.

Is Methylmalonic acid hazardous?

Methylmalonic acid has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Methylmalonic acid (CAS 516-05-2)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-47395-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.