Hydroflumethiazide

Also known as: Saluron, Diucardin, Flutizide, Glomerulin, Robezon, Spandiuril, Hidroalogen, Hidroflumetiazid, Diurometon, Elodrin, Elodrine, Finuret

Hydroflumethiazide (CAS 135-09-1) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C8H8F3N3O4S2 and a molecular weight of 331.29200 g/mol. Key properties include a melting point of 272-273ºC, a boiling point of 531.6ºC at 760 mmHg, a density of 1.678g/cm3 and a flash point of 275.3ºC. It is classified under GHS with signal word Danger and hazard statements H317 — May cause an allergic skin reaction and H334 — May cause allergy or asthma symptoms if inhaled. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 135-09-1
Jingsj CID: J-46787-2
Molecular Formula: C₈H₈F₃N₃O₄S₂
Molecular Weight: 331.29200 g/mol
Category: Organohalogen Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	272-273ºC
Boiling Point	531.6ºC at 760 mmHg
Density	1.678g/cm3
Flash Point	275.3ºC
Exact Mass	330.99100
PSA	135.12000
LogP	3.34280
Vapor Pressure	2.2E-11mmHg at 25°C
Refractive Index	1.55
Storage Conditions	Refrigerator

GHS Safety & Compliance

Health HazardSignal word: Danger

H317 — May cause an allergic skin reaction
H334 — May cause allergy or asthma symptoms if inhaled

Activity & Biological Data

Additional Information	[1]. Selvaag E, et al. Phototoxicity to sulphonamide derived oral antidiabetics and diuretics. Comparative in vitro and in vivo investigations. In Vivo. 1997 Jan-Feb;11(1):103-7. [2]. Brørs O, et al. Pharmacokinetics of a single oral dose of hydroflumethiazide in health and in cardiac failure.-. Eur J Clin Pharmacol. 1978 Nov 9;14(1):29-37. [3]. Hermansen K, et al. Effects of a thiazide diuretic (hydroflumethiazide) and a loop diuretic (bumetanide) on the endocrine pancreas: studies in vitro. Metabolism. 1985 Aug;34(8):784-9.

Additional Information

[1]. Selvaag E, et al. Phototoxicity to sulphonamide derived oral antidiabetics and diuretics. Comparative in vitro and in vivo investigations. In Vivo. 1997 Jan-Feb;11(1):103-7. [2]. Brørs O, et al. Pharmacokinetics of a single oral dose of hydroflumethiazide in health and in cardiac failure.-. Eur J Clin Pharmacol. 1978 Nov 9;14(1):29-37. [3]. Hermansen K, et al. Effects of a thiazide diuretic (hydroflumethiazide) and a loop diuretic (bumetanide) on the endocrine pancreas: studies in vitro. Metabolism. 1985 Aug;34(8):784-9.

Customs & Trade Information

HS Code	2935009090
Summary	2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Frequently Asked Questions

What is the CAS number of Hydroflumethiazide?

The CAS number of Hydroflumethiazide is 135-09-1.

What are the molecular formula and molecular weight of Hydroflumethiazide?

Hydroflumethiazide has molecular formula C8H8F3N3O4S2 and molecular weight 331.29200 g/mol.

Is Hydroflumethiazide hazardous?

Hydroflumethiazide has GHS signal word Danger and hazard statements H317 — May cause an allergic skin reaction; H334 — May cause allergy or asthma symptoms if inhaled.

What are the upstream and downstream products of Hydroflumethiazide?

For Hydroflumethiazide, Upstream Products: 4-Amino-6-(trifluoromethyl)benzene-1,3-disulfonamide, Formaldehyde.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Hydroflumethiazide (CAS 135-09-1)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-46787-2 (accessed 2026-11-07).

Data for reference only; verify product details with suppliers before purchase.