2-Methyl-6-(phenylethynyl)pyridine

Also known as: MPEP, 2-methyl-6-(2-phenylethynyl)pyridine, 2-methyl-6-phenylethynyl-pyridine, 6-Methyl-2-(phenylethynyl)pyridine, Pyridine, 2-methyl-6-(2-phenylethynyl)-

2-Methyl-6-(phenylethynyl)pyridine (CAS 96206-92-7) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C14H11N and a molecular weight of 193.24 g/mol. Key properties include a boiling point of 336.3ºC at 760mmHg and a flash point of 144.8ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 96206-92-7
Jingsj CID: J-46021-9
Molecular Formula: C₁₄H₁₁N
Molecular Weight: 193.24 g/mol
Category: Pharma Intermediates
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	336.3ºC at 760mmHg
Flash Point	144.8ºC
PSA	12.89000
LogP	3.59180
Storage Conditions	Desiccate at +4°C

Activity & Biological Data

Additional Information	[1]. D'Souza, Manoranjan S.; Markou, Athina Metabotropic glutamate receptor 5 antagonist 2-methyl-6-(phenylethynyl)pyridine (MPEP) microinfusions into the nucleus accumbens shell or ventral tegmental area attenuate the reinforcing effects of nicotine in rats. [2]. Chau, Peipei; Soederpalm, Bo; Ericson, Mia The mGluR5 antagonist MPEP elevates accumbal dopamine and glycine levels; interaction with strychnine-sensitive glycine receptors. Addiction Biology (2011), 16(4), 591-599. [3]. Inta, Dragos; Filipovic, Dragana; Lima-Ojeda, Juan M. et al. The mGlu5 receptor antagonist MPEP activates specific stress-related brain regions and lacks neurotoxic effects of the NMDA receptor antagonist MK-801: Significance for the use as anxiolytic/ant

Additional Information

[1]. D'Souza, Manoranjan S.; Markou, Athina Metabotropic glutamate receptor 5 antagonist 2-methyl-6-(phenylethynyl)pyridine (MPEP) microinfusions into the nucleus accumbens shell or ventral tegmental area attenuate the reinforcing effects of nicotine in rats. [2]. Chau, Peipei; Soederpalm, Bo; Ericson, Mia The mGluR5 antagonist MPEP elevates accumbal dopamine and glycine levels; interaction with strychnine-sensitive glycine receptors. Addiction Biology (2011), 16(4), 591-599. [3]. Inta, Dragos; Filipovic, Dragana; Lima-Ojeda, Juan M. et al. The mGlu5 receptor antagonist MPEP activates specific stress-related brain regions and lacks neurotoxic effects of the NMDA receptor antagonist MK-801: Significance for the use as anxiolytic/ant

Customs & Trade Information

HS Code	2933399090
Summary	2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 2-Methyl-6-(phenylethynyl)pyridine?

The CAS number of 2-Methyl-6-(phenylethynyl)pyridine is 96206-92-7.

What are the molecular formula and molecular weight of 2-Methyl-6-(phenylethynyl)pyridine?

2-Methyl-6-(phenylethynyl)pyridine has molecular formula C14H11N and molecular weight 193.24 g/mol.

What are the upstream and downstream products of 2-Methyl-6-(phenylethynyl)pyridine?

For 2-Methyl-6-(phenylethynyl)pyridine, Upstream Products: 2-Bromo-6-methylpyridine, 1-phenyl-2-(trimethylsilyl)acetylene, Phenylacetylene.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "2-Methyl-6-(phenylethynyl)pyridine (CAS 96206-92-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-46021-9 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.