6-Chloromelatonin

Also known as: 6-Cl-melatonin, Lopac-C-0331, Melatonin 6-Chloro Impurity, Melatonin Impurity 8, N-Acetyl-6-chloro-5-methoxytryptamine, N-[2-(6-Chloro-5-methoxy-1H-indol-3-yl)ethyl]acetamide, Acetamide, N-[2-(6-chloro-5-methoxy-1H-indol-3-yl)ethyl]-, Tocris-0443

6-Chloromelatonin (CAS 63762-74-3) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C13H15ClN2O2 and a molecular weight of 266.72300 g/mol. Key properties include a boiling point of 536.7ºC at 760 mmHg, a density of 1.272g/cm3 and a flash point of 278.4ºC. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 63762-74-3
Jingsj CID: J-46012-8
Molecular Formula: C₁₃H₁₅ClN₂O₂
Molecular Weight: 266.72300 g/mol
Category: Organohalogen Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	536.7ºC at 760 mmHg
Density	1.272g/cm3
Flash Point	278.4ºC
Exact Mass	266.08200
PSA	54.12000
LogP	2.89940
Refractive Index	1.608

Activity & Biological Data

Target	MT1:8.9 (pKi) MT2:9.1 (pKi)
Additional Information	[1]. Browning C, et al. Pharmacological characterization of human recombinant melatonin mt(1) and MT(2) receptors. Br J Pharmacol. 2000;129(5):877-886. [2]. Clemens JA, et al. Inhibition of luteinizing hormone release and ovulation by 6-chloro- and 6-fluoromelatonin. Neuroendocrinology. 1980;30(2):83-87. [3]. Vacas MI, et al. Binding sites for [3H]-melatonin in human platelets. J Pineal Res. 1992;13(2):60-65. [4]. Lanoix D, et al. Expression of melatoninergic receptors in human placental choriocarcinoma cell lines. Hum Reprod. 2006;21(8):1981-1989. [5]. Kennaway DJ, et al. A melatonin agonist and N-acetyl-N2-formyl-5-methoxykynurenamine accelerate the reentrainment of the melatonin rhythm following a phase advance of the light-dark cycle. Brain Res. 1989;495(2):349-354.

Target

MT1:8.9 (pKi) MT2:9.1 (pKi)

Additional Information

[1]. Browning C, et al. Pharmacological characterization of human recombinant melatonin mt(1) and MT(2) receptors. Br J Pharmacol. 2000;129(5):877-886. [2]. Clemens JA, et al. Inhibition of luteinizing hormone release and ovulation by 6-chloro- and 6-fluoromelatonin. Neuroendocrinology. 1980;30(2):83-87. [3]. Vacas MI, et al. Binding sites for [3H]-melatonin in human platelets. J Pineal Res. 1992;13(2):60-65. [4]. Lanoix D, et al. Expression of melatoninergic receptors in human placental choriocarcinoma cell lines. Hum Reprod. 2006;21(8):1981-1989. [5]. Kennaway DJ, et al. A melatonin agonist and N-acetyl-N2-formyl-5-methoxykynurenamine accelerate the reentrainment of the melatonin rhythm following a phase advance of the light-dark cycle. Brain Res. 1989;495(2):349-354.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of 6-Chloromelatonin?

The CAS number of 6-Chloromelatonin is 63762-74-3.

What are the molecular formula and molecular weight of 6-Chloromelatonin?

6-Chloromelatonin has molecular formula C13H15ClN2O2 and molecular weight 266.72300 g/mol.

What are the upstream and downstream products of 6-Chloromelatonin?

For 6-Chloromelatonin, Upstream Products: 2-Chloro-5-methylphenol, 2-Chloro-5-methyl-4-nitrophenol, 1-Chloro-2-methoxy-4-methyl-5-nitrobenzene.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "6-Chloromelatonin (CAS 63762-74-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-46012-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.