2-Methylsuccinic acid
Also known as: Methylsuccinic acid, 2-Methylbutanedioic acid, 1,2-Propanedicarboxylic acid, Pyrotartaric acid, DL-Methylsuccinic acid, (+/-)-Methylsuccinic acid, Methylbutanedioic acid, Butanedioic acid, 2-methyl-
2-Methylsuccinic acid (CAS 498-21-5) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C5H8O4 and a molecular weight of 132.115 g/mol. Key properties include a melting point of 110-115 °C(lit.), a boiling point of 236.5±13.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 111.1±16.3 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 498-21-5
- Jingsj CID
- J-45035-1
- Molecular Formula
- C5H8O4
- Molecular Weight
- 132.115 g/mol
- Category
- Organic Acids
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 110-115 °C(lit.) |
|---|---|
| Boiling Point | 236.5±13.0 °C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 111.1±16.3 °C |
| Exact Mass | 132.042252 |
| PSA | 74.60000 |
| LogP | -0.24 |
| Vapor Pressure | 0.0±1.0 mmHg at 25°C |
| Refractive Index | 1.474 |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Target | Human Endogenous Metabolite |
|---|---|
| Additional Information | [1]. Grosso S, et al. Ethylmalonic encephalopathy: further clinical and neuroradiological characterization. J Neurol. 2002 Oct;249(10):1446-50. [2]. Nowaczyk MJ, et al. Ethylmalonic and methylsuccinic aciduria in ethylmalonic encephalopathy arise from abnormal isoleucine metabolism. Metabolism. 1998 Jul;47(7):836-9. |
Customs & Trade Information
| HS Code | 2917190090 |
|---|---|
| Summary | 2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of 2-Methylsuccinic acid?
The CAS number of 2-Methylsuccinic acid is 498-21-5.
What are the molecular formula and molecular weight of 2-Methylsuccinic acid?
2-Methylsuccinic acid has molecular formula C5H8O4 and molecular weight 132.115 g/mol.
Is 2-Methylsuccinic acid hazardous?
2-Methylsuccinic acid has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
What are the upstream and downstream products of 2-Methylsuccinic acid?
For 2-Methylsuccinic acid, Upstream Products: Citraconic acid, Itaconic acid, 3-Methyl-1,5-pentanediol; Downstream Products: (R)-(+)-Methylsuccinic acid, Methylsuccinic anhydride, Water.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "2-Methylsuccinic acid (CAS 498-21-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-45035-1 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.