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2,2,2-Trifluoroethanesulfonyl chloride

Also known as: Ethanesulfonyl chloride, 2,2,2-trifluoro-, 2,2,2-Trifluoro-1-(thiophen-2-yl)ethan-1-amine, MFCD00007458, EINECS 216-713-7

2,2,2-Trifluoroethanesulfonyl chloride (CAS 1648-99-3) is a compound in the Organohalogen Compounds category listed in the Jingsj chemical database. It has the molecular formula C2H2ClF3O2S and a molecular weight of 182.549 g/mol. Key properties include a boiling point of 147.5±0.0 °C at 760 mmHg, a density of 1.7±0.1 g/cm3 and a flash point of 72.2±0.0 °C. It is classified under GHS with signal word Danger and hazard statements H314 — Causes severe skin burns and eye damage. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
1648-99-3
Jingsj CID
J-44756-3
Molecular Formula
C2H2ClF3O2S
Molecular Weight
182.549 g/mol
Category
Organohalogen Compounds
Last updated
8/21/2026

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Physicochemical Properties

Boiling Point147.5±0.0 °C at 760 mmHg
Density1.7±0.1 g/cm3
Flash Point72.2±0.0 °C
Exact Mass181.941605
PSA42.52000
LogP1.54
Vapor Pressure5.6±0.2 mmHg at 25°C
Refractive Index1.376

GHS Safety & Compliance

CorrosionSignal word: Danger
  • H314 — Causes severe skin burns and eye damage

Customs & Trade Information

HS Code2904909090
SummaryHS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 2,2,2-Trifluoroethanesulfonyl chloride?

The CAS number of 2,2,2-Trifluoroethanesulfonyl chloride is 1648-99-3.

What are the molecular formula and molecular weight of 2,2,2-Trifluoroethanesulfonyl chloride?

2,2,2-Trifluoroethanesulfonyl chloride has molecular formula C2H2ClF3O2S and molecular weight 182.549 g/mol.

Is 2,2,2-Trifluoroethanesulfonyl chloride hazardous?

2,2,2-Trifluoroethanesulfonyl chloride has GHS signal word Danger and hazard statements H314 — Causes severe skin burns and eye damage.

What are the upstream and downstream products of 2,2,2-Trifluoroethanesulfonyl chloride?

For 2,2,2-Trifluoroethanesulfonyl chloride, Upstream Products: Benzyl 2,2,2-trifluoroethyl sulfide, 2,2,2-Trifluoroethanethiol; Downstream Products: 4-[2-(1-Piperidinyl)ethoxy]benzoic acid hydrochloride, 2,2,2-Trifluoroethanesulfonamide.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "2,2,2-Trifluoroethanesulfonyl chloride (CAS 1648-99-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-44756-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.