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N-Methyl-N-(trimethylsilyl)trifluoroacetamide

Also known as: MSTFA, 2,2,2-Trifluoro-N-methyl-N-(trimethylsilyl)acetamide, N-Trimethylsilyl-N-methyl trifluoroacetamide, N-Methyl-N-trimethylsilyltrifluoroacetamide, Acetamide, 2,2,2-trifluoro-N-methyl-N-(trimethylsilyl)-, N-Methyl-N-(trimethylsilyl)trifluoroacetamide (MSTFA), MSTFA activated III

N-Methyl-N-(trimethylsilyl)trifluoroacetamide (CAS 24589-78-4) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C6H12F3NOSi and a molecular weight of 199.246 g/mol. Key properties include a melting point of 98-100°C, a boiling point of 131.0±0.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 28.0±25.9 °C. It is classified under GHS with signal word Warning and hazard statements H226 — Flammable liquid and vapour, H315 — Causes skin irritation and H319 — Causes serious eye irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
24589-78-4
Jingsj CID
J-44727-8
Molecular Formula
C6H12F3NOSi
Molecular Weight
199.246 g/mol
Category
Organic Bases
Last updated
8/21/2026

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Physicochemical Properties

Melting Point98-100°C
Boiling Point131.0±0.0 °C at 760 mmHg
Density1.1±0.1 g/cm3
Flash Point28.0±25.9 °C
Exact Mass199.064026
PSA20.31000
LogP2.09
Additional Property>1 (vs air)
Vapor Pressure9.5±0.2 mmHg at 25°C
Refractive Index1.381
Storage Conditions2-8℃
Additional Propertyreacts

GHS Safety & Compliance

Flammable / IrritantSignal word: Warning
  • H226 — Flammable liquid and vapour
  • H315 — Causes skin irritation
  • H319 — Causes serious eye irritation
  • H335 — May cause respiratory irritation

Customs & Trade Information

HS Code2931900090
Summary2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

Frequently Asked Questions

What is the CAS number of N-Methyl-N-(trimethylsilyl)trifluoroacetamide?

The CAS number of N-Methyl-N-(trimethylsilyl)trifluoroacetamide is 24589-78-4.

What are the molecular formula and molecular weight of N-Methyl-N-(trimethylsilyl)trifluoroacetamide?

N-Methyl-N-(trimethylsilyl)trifluoroacetamide has molecular formula C6H12F3NOSi and molecular weight 199.246 g/mol.

Is N-Methyl-N-(trimethylsilyl)trifluoroacetamide hazardous?

N-Methyl-N-(trimethylsilyl)trifluoroacetamide has GHS signal word Warning and hazard statements H226 — Flammable liquid and vapour; H315 — Causes skin irritation; H319 — Causes serious eye irritation.

What are the upstream and downstream products of N-Methyl-N-(trimethylsilyl)trifluoroacetamide?

For N-Methyl-N-(trimethylsilyl)trifluoroacetamide, Downstream Products: N-Methyl-2,2,2-trifluoroacetamide, Methyl 3-((trimethylsilyl)oxy)-2-butenoate, 4-(Trimethylsilyloxy)benzaldehyde.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "N-Methyl-N-(trimethylsilyl)trifluoroacetamide (CAS 24589-78-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-44727-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.