25-Hydroxycholesterol

Also known as: 5-Cholesten-3β,25-diol, Cholest-5-ene-3β,25-diol, 5-cholestene-3β,25-diol, Cholesterol 25-Hydroxy, 3β,25-Dihydroxycholest-5-ene, (3β)-Cholest-5-ene-3,25-diol, 25-Hydroxy Cholesterol, 5-CHOLESTEN-3-BETA, 25-DIOL, 5-CHOLESTENE-3BETA,25-DIOL, (3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-6-hydroxy-6-methylheptan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

25-Hydroxycholesterol (CAS 2140-46-7) is a compound in the Alcohols category listed in the Jingsj chemical database. It has the molecular formula C27H46O2 and a molecular weight of 402.653 g/mol. Key properties include a boiling point of 513.1±23.0 °C at 760 mmHg, a density of 1.0±0.1 g/cm3 and a flash point of 213.5±17.2 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed, H312 — Harmful in contact with skin and H315 — Causes skin irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 2140-46-7
Jingsj CID: J-44633-3
Molecular Formula: C₂₇H₄₆O₂
Molecular Weight: 402.653 g/mol
Category: Alcohols
Last updated: 8/21/2026

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Physicochemical Properties

Boiling Point	513.1±23.0 °C at 760 mmHg
Density	1.0±0.1 g/cm3
Flash Point	213.5±17.2 °C
Exact Mass	402.349792
PSA	40.46000
LogP	7.66
Vapor Pressure	0.0±3.0 mmHg at 25°C
Refractive Index	1.538
Storage Conditions	2-8℃

GHS Safety & Compliance

Irritant / Health HazardSignal word: Warning

H302 — Harmful if swallowed
H312 — Harmful in contact with skin
H315 — Causes skin irritation
H319 — Causes serious eye irritation
H332 — Harmful if inhaled
H335 — May cause respiratory irritation
H373 — May cause damage to organs through prolonged exposure

Activity & Biological Data

Target	Human Endogenous Metabolite
Additional Information	[1]. McDonald JG, et al. Editorial: 25-Hydroxycholesterol: a new life in immunology. J Leukoc Biol. 2010 Dec;88(6):1071-2.

Frequently Asked Questions

What is the CAS number of 25-Hydroxycholesterol?

The CAS number of 25-Hydroxycholesterol is 2140-46-7.

What are the molecular formula and molecular weight of 25-Hydroxycholesterol?

25-Hydroxycholesterol has molecular formula C27H46O2 and molecular weight 402.653 g/mol.

Is 25-Hydroxycholesterol hazardous?

25-Hydroxycholesterol has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H312 — Harmful in contact with skin; H315 — Causes skin irritation.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "25-Hydroxycholesterol (CAS 2140-46-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-44633-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.