Betamethasone
Also known as: 9α-Fluoro-16β-methylprednisolone, 16β-Methyl-9α-fluoroprednisolone, 9α-Fluoro-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadiene-3,20-dione, Flubenisolone, Celestone, β-Methasone, Betadexamethasone
Betamethasone (CAS 378-44-9) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C22H29FO5 and a molecular weight of 392.461 g/mol. Key properties include a melting point of 235-237°C, a boiling point of 568.2±50.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 297.5±30.1 °C. It is classified under GHS with signal word Danger and hazard statements H360 — May damage fertility or the unborn child and H373 — May cause damage to organs through prolonged exposure. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 378-44-9
- Jingsj CID
- J-44417-7
- Molecular Formula
- C22H29FO5
- Molecular Weight
- 392.461 g/mol
- Category
- Organic Compounds
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 235-237°C |
|---|---|
| Boiling Point | 568.2±50.0 °C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 297.5±30.1 °C |
| Exact Mass | 392.199890 |
| PSA | 94.83000 |
| LogP | 1.87 |
| Vapor Pressure | 0.0±3.5 mmHg at 25°C |
| Refractive Index | 1.592 |
GHS Safety & Compliance
- H360 — May damage fertility or the unborn child
- H373 — May cause damage to organs through prolonged exposure
Activity & Biological Data
| Additional Information | [1]. Arai, K., et al., Comparative study of the effects of betamethasone butyrate propionate, vitamin D3 derivatives, and cyclosporine on human lymphocyte-proliferation stimulated with a hemolytic streptococci-derived superantigen. Eur J Pharmacol, 2007. 571(2-3): p. 222-30. [2]. Dalziel, S.R., et al., Blood pressure at 6 years of age after prenatal exposure to betamethasone: follow-up results of a randomized, controlled trial. Pediatrics, 2004. 114(3): p. e373-7. [3]. Habib, G., et al., The effect of intra-articular injection of betamethasone acetate/betamethasone sodium phosphate at the knee joint on the hypothalamic-pituitary-adrenal axis: a case-controlled study. J Investig Med, 2013. 61(7): p. 1104-7. |
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Customs & Trade Information
| HS Code | 2937229000 |
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Frequently Asked Questions
What is the CAS number of Betamethasone?
The CAS number of Betamethasone is 378-44-9.
What are the molecular formula and molecular weight of Betamethasone?
Betamethasone has molecular formula C22H29FO5 and molecular weight 392.461 g/mol.
Is Betamethasone hazardous?
Betamethasone has GHS signal word Danger and hazard statements H360 — May damage fertility or the unborn child; H373 — May cause damage to organs through prolonged exposure.
What are the upstream and downstream products of Betamethasone?
For Betamethasone, Upstream Products: Betamethasone 21-acetate, Pregna-9(11),16-dien-20-one, 3-(acetyloxy)-, (3β,5α)-, (25R)-5α-Spirost-9(11)-en-3β-ol; Downstream Products: Betamethasone 17-valerate.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Betamethasone (CAS 378-44-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-44417-7 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.