Etoposide

Also known as: VP-16, VP 16, Vepeside, Toposar, Celltop, 4'-Demethylepipodophyllotoxin 9-(4,6-O-ethylidene-β-D-glucopyranoside), Etoposid, Etoposide (USP/INN/JAN)

Etoposide (CAS 33419-42-0) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C29H32O13 and a molecular weight of 588.557 g/mol. Key properties include a melting point of 236-251ºC, a boiling point of 798.1±60.0 °C at 760 mmHg, a density of 1.6±0.1 g/cm3 and a flash point of 263.6±26.4 °C. It is classified under GHS with signal word Danger and hazard statements H302 — Harmful if swallowed and H350 — May cause cancer. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 33419-42-0
Jingsj CID: J-44397-0
Molecular Formula: C₂₉H₃₂O₁₃
Molecular Weight: 588.557 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	236-251ºC
Boiling Point	798.1±60.0 °C at 760 mmHg
Density	1.6±0.1 g/cm3
Flash Point	263.6±26.4 °C
Exact Mass	588.184265
PSA	160.83000
LogP	0.30
Vapor Pressure	0.0±3.0 mmHg at 25°C
Refractive Index	1.662

GHS Safety & Compliance

Irritant / Health HazardSignal word: Danger

H302 — Harmful if swallowed
H350 — May cause cancer

Activity & Biological Data

Target	Topoisomerase II
Additional Information	[1]. Lee KI, et al. Etoposide induces pancreatic β-cells cytotoxicity via the JNK/ERK/GSK-3 signaling-mediated mitochondria-dependent apoptosis pathway. Toxicol In Vitro. 2016 Jul 26. pii: S0887-2333(16)30147-3. [2]. Calvani M, det al. Etoposide-Bevacizumab a new strategy against human melanoma cells expressing stem-like traits. Oncotarget. 2016 Jun 9. doi: 10.18632/oncotarget.9939. [3]. Fuchs, J., et al. Comparative activity of cisplatin, ifosfamide, doxorubicin, carboplatin, and etoposide in heterotransplanted hepatoblastoma. Cancer, 1998. 83(11): p. 2400-7.

Target

Topoisomerase II

Additional Information

[1]. Lee KI, et al. Etoposide induces pancreatic β-cells cytotoxicity via the JNK/ERK/GSK-3 signaling-mediated mitochondria-dependent apoptosis pathway. Toxicol In Vitro. 2016 Jul 26. pii: S0887-2333(16)30147-3. [2]. Calvani M, det al. Etoposide-Bevacizumab a new strategy against human melanoma cells expressing stem-like traits. Oncotarget. 2016 Jun 9. doi: 10.18632/oncotarget.9939. [3]. Fuchs, J., et al. Comparative activity of cisplatin, ifosfamide, doxorubicin, carboplatin, and etoposide in heterotransplanted hepatoblastoma. Cancer, 1998. 83(11): p. 2400-7.

Customs & Trade Information

HS Code	2932999099
Summary	2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Etoposide?

The CAS number of Etoposide is 33419-42-0.

What are the molecular formula and molecular weight of Etoposide?

Etoposide has molecular formula C29H32O13 and molecular weight 588.557 g/mol.

Is Etoposide hazardous?

Etoposide has GHS signal word Danger and hazard statements H302 — Harmful if swallowed; H350 — May cause cancer.

What are the upstream and downstream products of Etoposide?

For Etoposide, Upstream Products: 4'-demethylepipodophyllotoxin-9 beta-glucopyranoside, 1,1-Dimethoxyethane, 4'-Demethylepipodophyllotoxin; Downstream Products: 4'-demethylepipodophyllotoxin-9 beta-glucopyranoside.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Etoposide (CAS 33419-42-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-44397-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.