Lopinavir

Also known as: ABT 378, Aluviran, Koletra, (2S)-N-[(2R,4S,5S)-5-[[2-(2,6-dimethylphenoxy)acetyl]amino]-4-hydroxy-1,6-diphenylhexan-2-yl]-3-methyl-2-(2-oxo-1,3-diazinan-1-yl)butanamide

Lopinavir (CAS 192725-17-0) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C37H48N4O5 and a molecular weight of 628.801 g/mol. Key properties include a melting point of 124-127°C, a boiling point of 924.2±65.0 °C at 760 mmHg, a density of 1.2±0.1 g/cm3 and a flash point of 512.7±34.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 192725-17-0
Jingsj CID: J-44340-3
Molecular Formula: C₃₇H₄₈N₄O₅
Molecular Weight: 628.801 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	124-127°C
Boiling Point	924.2±65.0 °C at 760 mmHg
Density	1.2±0.1 g/cm3
Flash Point	512.7±34.3 °C
Exact Mass	628.362488
PSA	120.00000
LogP	6.26
Vapor Pressure	0.0±0.3 mmHg at 25°C
Refractive Index	1.577
Storage Conditions	Hygroscopic, -20°C Freezer, Under inert atmosphere
Stability	Hygroscopic

Activity & Biological Data

Additional Information	[1]. Vishnuvardhan, D., et al., Lopinavir: acute exposure inhibits P-glycoprotein; extended exposure induces P-glycoprotein. AIDS, 2003. 17(7): p. 1092-4. [2]. Gonzalez, L.M., et al., In vitro hypersusceptibility of human immunodeficiency virus type 1 subtype C protease to lopinavir. Antimicrob Agents Chemother, 2003. 47(9): p. 2817-22. [3]. Weemhoff, J.L., et al., Apparent mechanism-based inhibition of human CYP3A in-vitro by lopinavir. J Pharm Pharmacol, 2003. 55(3): p. 381-6. [4]. Sham, H.L., et al., ABT-378, a highly potent inhibitor of the human immunodeficiency virus protease. Antimicrob Agents Chemother, 1998. 42(12): p. 3218-24.

Additional Information

[1]. Vishnuvardhan, D., et al., Lopinavir: acute exposure inhibits P-glycoprotein; extended exposure induces P-glycoprotein. AIDS, 2003. 17(7): p. 1092-4. [2]. Gonzalez, L.M., et al., In vitro hypersusceptibility of human immunodeficiency virus type 1 subtype C protease to lopinavir. Antimicrob Agents Chemother, 2003. 47(9): p. 2817-22. [3]. Weemhoff, J.L., et al., Apparent mechanism-based inhibition of human CYP3A in-vitro by lopinavir. J Pharm Pharmacol, 2003. 55(3): p. 381-6. [4]. Sham, H.L., et al., ABT-378, a highly potent inhibitor of the human immunodeficiency virus protease. Antimicrob Agents Chemother, 1998. 42(12): p. 3218-24.

Frequently Asked Questions

What is the CAS number of Lopinavir?

The CAS number of Lopinavir is 192725-17-0.

What are the molecular formula and molecular weight of Lopinavir?

Lopinavir has molecular formula C37H48N4O5 and molecular weight 628.801 g/mol.

What are the upstream and downstream products of Lopinavir?

For Lopinavir, Upstream Products: N-[(1S,2S,4S)-4-amino-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-2-(2,6-dimethylphenoxy)acetamide, (2S)-3-methyl-2-(2-oxotetrahydropyrimidin-1(2H)-yl)butanoic acid, L-Valine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Lopinavir (CAS 192725-17-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-44340-3 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.