Bicalutamide
Also known as: Casodex, Cosudex, ICI-176334, ZD-176334, (R,S)-Bicalutamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide, Propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl-
Bicalutamide (CAS 90357-06-5) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C18H14F4N2O4S and a molecular weight of 430.373 g/mol. Key properties include a melting point of 191-193°C, a boiling point of 650.3±55.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 347.1±31.5 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 90357-06-5
- Jingsj CID
- J-44326-9
- Molecular Formula
- C18H14F4N2O4S
- Molecular Weight
- 430.373 g/mol
- Category
- Organic Bases
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 191-193°C |
|---|---|
| Boiling Point | 650.3±55.0 °C at 760 mmHg |
| Density | 1.5±0.1 g/cm3 |
| Flash Point | 347.1±31.5 °C |
| Exact Mass | 430.061035 |
| PSA | 115.64000 |
| LogP | 4.94 |
| Vapor Pressure | 0.0±2.0 mmHg at 25°C |
| Refractive Index | 1.578 |
| Storage Conditions | Store at RT |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Additional Information | [1]. Nicola J. Clegg,1 John Wongvipat,1,2 Jim Joseph, ARN-509: a novel anti-androgen for prostate cancer treatment. Cancer Res. 2012 March 15; 72(6): 1494-1503. [2]. RACHEL M. SQUILLACE, DAVID MILLER, SCOTT D. WARDWELL, Synergistic activity of the mTOR inhibitor ridaforolimus and the antiandrogen bicalutamide in prostate cancer models. Int J Oncol. 2012 August; 41(2): 425-432. [3]. Nakabayashi M, Werner L, Courtney KD, Phase II trial of RAD001 and bicalutamide for castration-resistant prostate cancer. BJU Int. 2012 Dec;110(11):1729-35. |
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Customs & Trade Information
| HS Code | 2929909090 |
|---|---|
| Summary | 2929909090 other compounds with other nitrogen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of Bicalutamide?
The CAS number of Bicalutamide is 90357-06-5.
What are the molecular formula and molecular weight of Bicalutamide?
Bicalutamide has molecular formula C18H14F4N2O4S and molecular weight 430.373 g/mol.
Is Bicalutamide hazardous?
Bicalutamide has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
What are the upstream and downstream products of Bicalutamide?
For Bicalutamide, Upstream Products: N-[4-Cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)thio]-2-hydroxy-2-methylpropanamide, 4-Fluorothiophenol, N-[4-Cyano-3-(trifluoromethyl)phenyl]-2-methyloxirane-2-carboxamide.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Bicalutamide (CAS 90357-06-5)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-44326-9 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.