Acyclovir

Also known as: Aciclovir, Acycloguanosine, 9-(2-Hydroxyethoxy)methylguanine, 2-Amino-9-[(2-hydroxyethoxy)methyl]-1,9-dihydro-6H-purin-6-one, BW 248U, Zovirax, Zoviax, Cycloviran, Herpevir, Vipral, Virorax

Acyclovir (CAS 59277-89-3) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C8H11N5O3 and a molecular weight of 225.205 g/mol. Key properties include a melting point of 256-257°C, a boiling point of 576.5±58.0 °C at 760 mmHg, a density of 1.8±0.1 g/cm3 and a flash point of 302.4±32.3 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 59277-89-3
Jingsj CID: J-44222-8
Molecular Formula: C₈H₁₁N₅O₃
Molecular Weight: 225.205 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	256-257°C
Boiling Point	576.5±58.0 °C at 760 mmHg
Density	1.8±0.1 g/cm3
Flash Point	302.4±32.3 °C
Exact Mass	225.086182
PSA	119.05000
LogP	-3.31
Vapor Pressure	0.0±1.7 mmHg at 25°C
Refractive Index	1.762
Storage Conditions	-20℃
Additional Property	H2O: 0.7 mg/mL

Activity & Biological Data

Additional Information	[1]. Li Z, et al. Acyclovir treatment of skin lesions results in immune deviation in mice infected cutaneously with herpes simplex virus. Antivir Chem Chemother. 1999 Sep;10(5):251-7. [2]. Shelley WB, Hashim M, Shelley ED. Acyclovir in the treatment of hand-foot-and-mouth disease. Cutis. 1996 Apr;57(4):232-4. [3]. Collins P, Oliver NM. Sensitivity monitoring of herpes simplex virus isolates from patients receiving acyclovir. J Antimicrob Chemother. 1986 Oct;18 Suppl B:103-12. [4]. Meyrick Thomas RH, Dodd HJ, Yeo JM, Oral acyclovir in the suppression of recurrent non-genital herpes simplex virus infection. Br J Dermatol. 1985 Dec;113(6):731-5. [5]. Tang IY, Maddux MS, Veremis SA, Low-dose oral acyclovir for prevention of herpes simplex virus infection during OKT3 therapy. Transplant Proc. 1989 Feb;21(1 Pt 2):1758-60.

Additional Information

[1]. Li Z, et al. Acyclovir treatment of skin lesions results in immune deviation in mice infected cutaneously with herpes simplex virus. Antivir Chem Chemother. 1999 Sep;10(5):251-7. [2]. Shelley WB, Hashim M, Shelley ED. Acyclovir in the treatment of hand-foot-and-mouth disease. Cutis. 1996 Apr;57(4):232-4. [3]. Collins P, Oliver NM. Sensitivity monitoring of herpes simplex virus isolates from patients receiving acyclovir. J Antimicrob Chemother. 1986 Oct;18 Suppl B:103-12. [4]. Meyrick Thomas RH, Dodd HJ, Yeo JM, Oral acyclovir in the suppression of recurrent non-genital herpes simplex virus infection. Br J Dermatol. 1985 Dec;113(6):731-5. [5]. Tang IY, Maddux MS, Veremis SA, Low-dose oral acyclovir for prevention of herpes simplex virus infection during OKT3 therapy. Transplant Proc. 1989 Feb;21(1 Pt 2):1758-60.

Customs & Trade Information

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Frequently Asked Questions

What is the CAS number of Acyclovir?

The CAS number of Acyclovir is 59277-89-3.

What are the molecular formula and molecular weight of Acyclovir?

Acyclovir has molecular formula C8H11N5O3 and molecular weight 225.205 g/mol.

What are the upstream and downstream products of Acyclovir?

For Acyclovir, Upstream Products: 9-[(2-Acetoxyethoxy)methyl]-N2-acetylguanine, 1,3-Dioxolane, Guanine; Downstream Products: 2-[(2-amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]ethyl N-(tert-butoxycarbonyl)-L-valinate, Guanine, Acyclovir EP Impurity A.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Acyclovir (CAS 59277-89-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-44222-8 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.