3,4-Dihydro-7-hydroxy-2(1H)-quinolinone
Also known as: 7-Hydroxy-3,4-dihydro-2(1H)-quinolinone, 7-Hydroxycarbostyril, 7-Hydroxy-3,4-dihydrocarbostyril, 7-Hydroxy-2-oxo-1,2,3,4-tetrahydroquinoline, Aripiprazole impurity O, Aripiprazole dihydroquinolinone impurity, Intermediate of Aripiprazole, 7-Hydroxy-3,4-dihydro-2(1H)-chinolinon, 7-Hydroxy-3,4-dihydroquinolin-2(1H)-one
3,4-Dihydro-7-hydroxy-2(1H)-quinolinone (CAS 22246-18-0) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C9H9NO2 and a molecular weight of 163.173 g/mol. Key properties include a melting point of 233-237 °C, a boiling point of 403.7±45.0 °C at 760 mmHg, a density of 1.3±0.1 g/cm3 and a flash point of 198.0±28.7 °C. It is classified under GHS with signal word Warning and hazard statements H302 — Harmful if swallowed and H317 — May cause an allergic skin reaction. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 22246-18-0
- Jingsj CID
- J-44158-7
- Molecular Formula
- C9H9NO2
- Molecular Weight
- 163.173 g/mol
- Category
- Pharma Intermediates
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 233-237 °C |
|---|---|
| Boiling Point | 403.7±45.0 °C at 760 mmHg |
| Density | 1.3±0.1 g/cm3 |
| Flash Point | 198.0±28.7 °C |
| Exact Mass | 163.063324 |
| PSA | 49.33000 |
| LogP | 0.99 |
| Vapor Pressure | 0.0±1.0 mmHg at 25°C |
| Refractive Index | 1.604 |
GHS Safety & Compliance
- H302 — Harmful if swallowed
- H317 — May cause an allergic skin reaction
Activity & Biological Data
| Target | IC50: 183 μM (MAO-A)[1] |
|---|---|
| Additional Information | [1]. Meiring L, et al. Inhibition of monoamine oxidase by 3,4-dihydro-2(1H)-quinolinone derivatives. Bioorg Med Chem Lett. 2013 Oct 15;23(20):5498-502. |
Customs & Trade Information
| HS Code | 2933790090 |
|---|---|
| Summary | 2933790090. other lactams. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:9.0%. General tariff:20.0% |
Frequently Asked Questions
What is the CAS number of 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone?
The CAS number of 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone is 22246-18-0.
What are the molecular formula and molecular weight of 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone?
3,4-Dihydro-7-hydroxy-2(1H)-quinolinone has molecular formula C9H9NO2 and molecular weight 163.173 g/mol.
Is 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone hazardous?
3,4-Dihydro-7-hydroxy-2(1H)-quinolinone has GHS signal word Warning and hazard statements H302 — Harmful if swallowed; H317 — May cause an allergic skin reaction.
What are the upstream and downstream products of 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone?
For 3,4-Dihydro-7-hydroxy-2(1H)-quinolinone, Upstream Products: 3-Chloro-N-(3-hydroxyphenyl)propanamide, m-Anisidine, 3-Chloropropionyl chloride; Downstream Products: 7-Hydroxy-1,2,3,4-tetrahydroquinoline, Aripiprazole, 7-(4-Bromobutoxy)-3,4-dihydro-2(1H)-quinolinone.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "3,4-Dihydro-7-hydroxy-2(1H)-quinolinone (CAS 22246-18-0)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-44158-7 (accessed 2026-11-09).
Data for reference only; verify product details with suppliers before purchase.