Hydroxyflutamide
Also known as: 2-Hydroxyflutamide, 2-Hydroxy-2-methyl-N-(4-nitro-3-(trifluoromethyl)phenyl)propanamide, 2-Hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide, 2-Hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propionamide, 2-Hydroxy-flutamide, 2-hydroxy Flutamide, Hydroxy Flutamide, Hydroxy-Flutamide(Flutamide metabolite), hydroxyniphtholide, Propanamide, 2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-, SCH 16423, a,a,a-Trifluoro-2-methyl-4'-nitro-m-lactotoluidide, CS-1970
Hydroxyflutamide (CAS 52806-53-8) is a compound in the Organic Bases category listed in the Jingsj chemical database. It has the molecular formula C11H11F3N2O4 and a molecular weight of 292.211 g/mol. Key properties include a melting point of 125-130℃, a boiling point of 443.8±45.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 222.2±28.7 °C. It is classified under GHS with signal word Warning and hazard statements H315 — Causes skin irritation, H319 — Causes serious eye irritation and H335 — May cause respiratory irritation. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.
- CAS No.
- 52806-53-8
- Jingsj CID
- J-43448-3
- Molecular Formula
- C11H11F3N2O4
- Molecular Weight
- 292.211 g/mol
- Category
- Organic Bases
- Last updated
- 8/21/2026
No offers for this compound yet.
Request a quotePhysicochemical Properties
| Melting Point | 125-130℃ |
|---|---|
| Boiling Point | 443.8±45.0 °C at 760 mmHg |
| Density | 1.5±0.1 g/cm3 |
| Flash Point | 222.2±28.7 °C |
| Exact Mass | 292.067078 |
| PSA | 95.15000 |
| LogP | 3.16 |
| Vapor Pressure | 0.0±1.1 mmHg at 25°C |
| Refractive Index | 1.546 |
GHS Safety & Compliance
- H315 — Causes skin irritation
- H319 — Causes serious eye irritation
- H335 — May cause respiratory irritation
Activity & Biological Data
| Target | IC50: 700 nM (androgen receptor)[1] |
|---|---|
| Additional Information | [1]. Furr BJ, et, al. Casodex: preclinical studies and controversies. Ann N Y Acad Sci. 1995 Jun 12;761:79-96. [2]. Liu HL, et, al. A Molecular Modeling Study of the Hydroxyflutamide Resistance Mechanism Induced by Androgen Receptor Mutations. Int J Mol Sci. 2017 Aug 23;18(9):1823. |
Customs & Trade Information
| HS Code | 2924299090 |
|---|---|
| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |
Frequently Asked Questions
What is the CAS number of Hydroxyflutamide?
The CAS number of Hydroxyflutamide is 52806-53-8.
What are the molecular formula and molecular weight of Hydroxyflutamide?
Hydroxyflutamide has molecular formula C11H11F3N2O4 and molecular weight 292.211 g/mol.
Is Hydroxyflutamide hazardous?
Hydroxyflutamide has GHS signal word Warning and hazard statements H315 — Causes skin irritation; H319 — Causes serious eye irritation; H335 — May cause respiratory irritation.
What are the upstream and downstream products of Hydroxyflutamide?
For Hydroxyflutamide, Upstream Products: Methyl 2-hydroxyisobutyrate, 4-Nitro-3-(trifluoromethyl)aniline, 4-Nitro-3-(trifluoromethyl)phenol.
Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.
Last updated:
How to cite: Jingsj. "Hydroxyflutamide (CAS 52806-53-8)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-43448-3 (accessed 2026-11-06).
Data for reference only; verify product details with suppliers before purchase.