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N-Succinimidyl 3-(2-pyridyldithio)propionate

Also known as: 3-(2-Pyridyldithio)propionic acid N-hydroxysuccinimide ester, 2,5-dioxopyrrolidin-1-yl 3-(pyridin-2-yldisulfanyl)propanoate, Succinimidyl 3-(2-pyridyldithio)propionate, SPDP crosslinker, N-Hydroxysuccinimidyl 3-(2-pyridyldithio)propionate, NSC 344485, NSC 677449, 1-[1-Oxo-3-(2-pyridyldithio)propoxy]pyrrolidine-2,5-dione

N-Succinimidyl 3-(2-pyridyldithio)propionate (CAS 68181-17-9) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C12H12N2O4S2 and a molecular weight of 312.365 g/mol. Key properties include a melting point of 84-86 °C(lit.), a boiling point of 465.9±55.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 235.6±31.5 °C. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
68181-17-9
Jingsj CID
J-42999-2
Molecular Formula
C12H12N2O4S2
Molecular Weight
312.365 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Melting Point84-86 °C(lit.)
Boiling Point465.9±55.0 °C at 760 mmHg
Density1.5±0.1 g/cm3
Flash Point235.6±31.5 °C
Exact Mass312.023834
PSA127.17000
LogP0.99
Vapor Pressure0.0±1.2 mmHg at 25°C
Refractive Index1.650
Additional Propertyacetone: 50 mg/mL

Activity & Biological Data

Additional Information[1]. Lobedanz S et al. A periplasmic coiled-coil interface underlying TolC recruitment and the assembly of bacterial drug effluxpumps. Proc Natl Acad Sci U S A, 2007 Mar 13, 104(11):4612-7. [2]. Karumuthil-Melethil S et al. Dendritic cell-directed CTLA-4 engagement during pancreatic beta cell antigen presentation delays type 1diabetes. J Immunol 2010 Jun 15, 184(12):6695-708.

Frequently Asked Questions

What is the CAS number of N-Succinimidyl 3-(2-pyridyldithio)propionate?

The CAS number of N-Succinimidyl 3-(2-pyridyldithio)propionate is 68181-17-9.

What are the molecular formula and molecular weight of N-Succinimidyl 3-(2-pyridyldithio)propionate?

N-Succinimidyl 3-(2-pyridyldithio)propionate has molecular formula C12H12N2O4S2 and molecular weight 312.365 g/mol.

What are the upstream and downstream products of N-Succinimidyl 3-(2-pyridyldithio)propionate?

For N-Succinimidyl 3-(2-pyridyldithio)propionate, Upstream Products: N-Hydroxysuccinimide, 3-(2-Pyridyldithio)propanoic acid, 2,2'-Dithiodipyridine.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "N-Succinimidyl 3-(2-pyridyldithio)propionate (CAS 68181-17-9)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-42999-2 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.