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Mafenide hydrochloride

Also known as: 4-(Aminomethyl)benzenesulfonamide hydrochloride, Homosulfamine hydrochloride, Marfanil hydrochloride, Sulfamylon hydrochloride, α-Amino-p-toluenesulfonamide hydrochloride, 4-Aminomethylbenzenesulfonamide hydrochloride, p-(Aminomethyl)benzenesulfonamide hydrochloride, Benzenesulfonamide, 4-(aminomethyl)-, monohydrochloride, Mafenide HCl, Masudin, Morfanil

Mafenide hydrochloride (CAS 138-37-4) is a compound in the Pharma Intermediates category listed in the Jingsj chemical database. It has the molecular formula C7H11ClN2O2S and a molecular weight of 222.692 g/mol. Key properties include a melting point of 261-263 °C(lit.), a boiling point of 382ºC at 760mmHg and a flash point of 184.8ºC. It is classified under GHS with signal word Warning and hazard statements H317 — May cause an allergic skin reaction. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
138-37-4
Jingsj CID
J-42457-2
Molecular Formula
C7H11ClN2O2S
Molecular Weight
222.692 g/mol
Category
Pharma Intermediates
Last updated
8/21/2026

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Physicochemical Properties

Melting Point261-263 °C(lit.)
Boiling Point382ºC at 760mmHg
Flash Point184.8ºC
Exact Mass222.022980
PSA94.56000
LogP3.07610

GHS Safety & Compliance

IrritantSignal word: Warning
  • H317 — May cause an allergic skin reaction

Activity & Biological Data

Additional Information[1]. Siuda, J.F. and C.D. Cihonski, New compounds: carbamate derivatives of mafenide (homosulfanilamide). J Pharm Sci, 1972. 61(11): p. 1856-7. [2]. Haynes, B.W., Jr., Mafenide acetate in burn treatment. N Engl J Med, 1971. 284(23): p. 1324. [3]. Haik, J., et al., Burn care standards in Israel: lack of consensus. Burns, 2005. 31(7): p. 845-9.

Customs & Trade Information

HS Code2935009090
Summary2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Frequently Asked Questions

What is the CAS number of Mafenide hydrochloride?

The CAS number of Mafenide hydrochloride is 138-37-4.

What are the molecular formula and molecular weight of Mafenide hydrochloride?

Mafenide hydrochloride has molecular formula C7H11ClN2O2S and molecular weight 222.692 g/mol.

Is Mafenide hydrochloride hazardous?

Mafenide hydrochloride has GHS signal word Warning and hazard statements H317 — May cause an allergic skin reaction.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "Mafenide hydrochloride (CAS 138-37-4)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-42457-2 (accessed 2026-11-06).

Data for reference only; verify product details with suppliers before purchase.