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2-Ketoglutaric acid

Also known as: 2-Oxoglutaric acid, 2-Oxopentanedioic acid, alpha-Ketoglutaric acid, α-Ketoglutaric acid, 2-Oxo-1,5-pentanedioic acid, 2-Oxo-Glutaric Acid, Oxoglutaric acid, Ketoglutaric acid, Pentanedioic acid, 2-oxo-, Glutaric acid, 2-oxo-

2-Ketoglutaric acid (CAS 328-50-7) is a compound in the Organic Acids category listed in the Jingsj chemical database. It has the molecular formula C5H6O5 and a molecular weight of 146.098 g/mol. Key properties include a melting point of 113-115 °C, a boiling point of 345.6±25.0 °C at 760 mmHg, a density of 1.5±0.1 g/cm3 and a flash point of 177.0±19.7 °C. It is classified under GHS with signal word Danger and hazard statements H318 — Causes serious eye damage. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.
328-50-7
Jingsj CID
J-42426-0
Molecular Formula
C5H6O5
Molecular Weight
146.098 g/mol
Category
Organic Acids
Last updated
8/21/2026

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Physicochemical Properties

Melting Point113-115 °C
Boiling Point345.6±25.0 °C at 760 mmHg
Density1.5±0.1 g/cm3
Flash Point177.0±19.7 °C
Exact Mass146.021530
PSA91.67000
LogP-1.43
Vapor Pressure0.0±1.6 mmHg at 25°C
Refractive Index1.494
Storage Conditions2-8°C

GHS Safety & Compliance

CorrosionSignal word: Danger
  • H318 — Causes serious eye damage

Activity & Biological Data

TargetHuman Endogenous Metabolite
Additional Information[1]. Rocchiccioli F, et al. Microdetermination of 2-ketoglutaric acid in plasma and cerebrospinal fluid by capillary gas chromatography mass spectrometry; application to pediatrics. Biomed Mass Spectrom. 1984 Jan;11(1):24-8.

Customs & Trade Information

HS Code2918300090
Summary2918300090 other carboxylic acids with aldehyde or ketone function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%

Frequently Asked Questions

What is the CAS number of 2-Ketoglutaric acid?

The CAS number of 2-Ketoglutaric acid is 328-50-7.

What are the molecular formula and molecular weight of 2-Ketoglutaric acid?

2-Ketoglutaric acid has molecular formula C5H6O5 and molecular weight 146.098 g/mol.

Is 2-Ketoglutaric acid hazardous?

2-Ketoglutaric acid has GHS signal word Danger and hazard statements H318 — Causes serious eye damage.

What are the upstream and downstream products of 2-Ketoglutaric acid?

For 2-Ketoglutaric acid, Upstream Products: 5-Hydroxymethylfurfural, 2-Furoic acid, 2,5-Furandicarboxylic acid; Downstream Products: Hydroxypyruvic acid, L-Glutamic acid, Oxaloacetic acid.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated:

How to cite: Jingsj. "2-Ketoglutaric acid (CAS 328-50-7)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-42426-0 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.