Prostaglandin E1

Also known as: Alprostadil, PGE1, (11α,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid, Caverject, Liple, Minprog, Palux, Topiglan, Prost-13-en-1-oic acid, 11,15-dihydroxy-9-oxo-, (11α,13E,15S)-

Prostaglandin E1 (CAS 745-65-3) is a compound in the Organic Compounds category listed in the Jingsj chemical database. It has the molecular formula C20H34O5 and a molecular weight of 354.481 g/mol. Key properties include a melting point of 115-116 °C, a boiling point of 529.3±50.0 °C at 760 mmHg, a density of 1.1±0.1 g/cm3 and a flash point of 288.0±26.6 °C. It is classified under GHS with signal word Danger and hazard statements H301 — Toxic if swallowed and H361 — Suspected of damaging fertility or the unborn child. No supplier offers are currently listed; request a quote. Record last updated Aug 21, 2026.

CAS No.: 745-65-3
Jingsj CID: J-42177-2
Molecular Formula: C₂₀H₃₄O₅
Molecular Weight: 354.481 g/mol
Category: Organic Compounds
Last updated: 8/21/2026

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Physicochemical Properties

Melting Point	115-116 °C
Boiling Point	529.3±50.0 °C at 760 mmHg
Density	1.1±0.1 g/cm3
Flash Point	288.0±26.6 °C
Exact Mass	354.240631
PSA	94.83000
LogP	2.24
Vapor Pressure	0.0±3.2 mmHg at 25°C
Refractive Index	1.546

GHS Safety & Compliance

Acute Toxicity / Health HazardSignal word: Danger

H301 — Toxic if swallowed
H361 — Suspected of damaging fertility or the unborn child

Activity & Biological Data

Target	Human Endogenous Metabolite
Additional Information	[1]. Cawello W, et al. Dose proportional pharmacokinetics of alprostadil (prostaglandin E1) in healthy volunteers following intravenous infusion. Br J Clin Pharmacol. 1995 Sep;40(3):273-6. [2]. Roehl SL, et al. Alprostadil (Prostin VR Pediatric Sterile Solution, The Upjohn Company). Drug Intell Clin Pharm. 1982 Nov;16(11):823-32. [3]. Harding LM, et al. Comparison of a needle-free high-pressure injection system with needle-tipped injection of intracavernosal alprostadil for erectile dysfunction. Int J Impot Res. 2002 Dec;14(6):498-501.

Target

Human Endogenous Metabolite

Additional Information

[1]. Cawello W, et al. Dose proportional pharmacokinetics of alprostadil (prostaglandin E1) in healthy volunteers following intravenous infusion. Br J Clin Pharmacol. 1995 Sep;40(3):273-6. [2]. Roehl SL, et al. Alprostadil (Prostin VR Pediatric Sterile Solution, The Upjohn Company). Drug Intell Clin Pharm. 1982 Nov;16(11):823-32. [3]. Harding LM, et al. Comparison of a needle-free high-pressure injection system with needle-tipped injection of intracavernosal alprostadil for erectile dysfunction. Int J Impot Res. 2002 Dec;14(6):498-501.

Customs & Trade Information

HS Code	29375000

Frequently Asked Questions

What is the CAS number of Prostaglandin E1?

The CAS number of Prostaglandin E1 is 745-65-3.

What are the molecular formula and molecular weight of Prostaglandin E1?

Prostaglandin E1 has molecular formula C20H34O5 and molecular weight 354.481 g/mol.

Is Prostaglandin E1 hazardous?

Prostaglandin E1 has GHS signal word Danger and hazard statements H301 — Toxic if swallowed; H361 — Suspected of damaging fertility or the unborn child.

Data compiled from public chemical databases such as PubChem and supplier catalogs; supplier offers are provided by suppliers.

Last updated: 8/21/2026

How to cite: Jingsj. "Prostaglandin E1 (CAS 745-65-3)". Jingsj Chemical Database. https://www.jingsj.com/compound/J-42177-2 (accessed 2026-11-09).

Data for reference only; verify product details with suppliers before purchase.